Catalog No.
PMC35501
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse Cyp21 (Leu30-Arg476).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Steroid 21-hydroxylase, 1.14.14.16, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21, Cyp21, Cyp21a-1, Cyp21a1
Purification
Purified by antigen affinity column.
Accession
P03940
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Diagnostic Value of Autoantibodies against Steroidogenic Enzymes and Hormones in Infertile Women with Premature Ovarian Insufficiency., PMID:38928251
Relation between HLA and copy number variation of steroid 21-hydroxylase in a Swedish cohort of patients with autoimmune Addison's disease., PMID:37553728
The effect of etanercept therapy on adrenal steroid metabolism in juvenile idiopathic arthritis: a steroid metabolomics approach., PMID:37046333
Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid., PMID:31726965
Measurement of serum tenascin-X in patients with congenital adrenal hyperplasia at risk for Ehlers-Danlos contiguous gene deletion syndrome CAH-X., PMID:31666125
Overexpression of Golgi Protein CYP21-4s Improves Crop Productivity in Potato and Rice by Increasing the Abundance of Mannosidic Glycoproteins., PMID:28775727
Secondary amenorrhoea associated with high serum 17-hydroxyprogesterone levels revealing a heterozygous CYP21A2 mutation in a woman with Addison disease., PMID:25353971
ACTH receptor blockade: a novel approach to treat congenital adrenal hyperplasia, or Cushing's disease., PMID:19931309
Molecular basis of complete complement C4 deficiency in two North-African families with systemic lupus erythematosus., PMID:19279649
A case of 3beta-hydroxysteroid dehydrogenase type II (HSD3B2) deficiency picked up by neonatal screening for 21-hydroxylase deficiency: difficulties and delay in etiologic diagnosis., PMID:17496421
Molecular identification of adrenal inner zone antigen as a heme-binding protein., PMID:16279947
Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2., PMID:15747502
Genetic, structural and functional diversities of human complement components C4A and C4B and their mouse homologues, Slp and C4., PMID:11367523
Organ-specific and non-organ-specific autoantibodies in children and young adults with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)., PMID:11022196
Target proteins in human autoimmunity: cytochromes P450 and UDP- glucuronosyltransferases., PMID:10851284
Sp1-like proteins function in the transcription of human ferredoxin genes., PMID:10754389
Expression and zonal distribution of CYP2D16 in the guinea pig adrenal cortex: relationship to xenobiotic metabolism., PMID:8643085
Isolation and sequence of a cDNA encoding the Jerusalem artichoke cinnamate 4-hydroxylase, a major plant cytochrome P450 involved in the general phenylpropanoid pathway., PMID:8097885
For research use only. Not for human or drug use.
