Catalog No.
PHJ91001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human POMT1 (Pro318-His513).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
POMT1,Dolichyl-phosphate-mannose--protein mannosyltransferase 1,Protein O-mannosyl-transferase 1
Purification
Purified by antigen affinity column.
Accession
Q9Y6A1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Deletion of POMT2 in Zebrafish Causes Degeneration of Photoreceptors., PMID:36499139
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Utility of Immunohistochemistry and Western Blot in Profiling Clinically Suspected Cases of Congenital Muscular Dystrophy., PMID:34220063
Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1., PMID:33863907
Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion., PMID:24297939
Differential glycosylation of α-dystroglycan and proteins other than α-dystroglycan by like-glycosyltransferase., PMID:21930648
Protein O-mannosylation is necessary for normal embryonic development in zebrafish., PMID:20466645
A comparative study of alpha-dystroglycan glycosylation in dystroglycanopathies suggests that the hypoglycosylation of alpha-dystroglycan does not consistently correlate with clinical severity., PMID:18691338
Genes required for functional glycosylation of dystroglycan are conserved in zebrafish., PMID:18632251
Diagnosis and etiology of congenital muscular dystrophy., PMID:18160674
Efficient antibody production upon suppression of O mannosylation in the yeast Ogataea minuta., PMID:18039826
Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndrome., PMID:17456771
The congenital muscular dystrophies: recent advances and molecular insights., PMID:17163796
Intracellular binding of fukutin and alpha-dystroglycan: relation to glycosylation of alpha-dystroglycan., PMID:17005282
The twisted abdomen phenotype of Drosophila POMT1 and POMT2 mutants coincides with their heterophilic protein O-mannosyltransferase activity., PMID:15271988
POMT1 mutation results in defective glycosylation and loss of laminin-binding activity in alpha-DG., PMID:15037715
Mutations in the human LARGE gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan., PMID:12966029
Characterization of POMT2, a novel member of the PMT protein O-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids., PMID:12460945
For research use only. Not for human or drug use.
