Catalog No.
PHN51901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IGLC1 (Gly1-Thr95).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Immunoglobulin lambda constant 1, Ig lambda chain C region MGC, Ig lambda-1 chain C region, IGLC1
Purification
Purified by antigen affinity column.
Accession
P0CG04
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Germline polymorphism in the immunoglobulin kappa and lambda loci explain variation in the expressed light chain antibody repertoire., PMID:40501977
Human genetic variation shapes the antibody repertoire across B cell development., PMID:40475565
Comparison of middle molecule removal with expanded hemodialysis versus haemodiafiltration among Chinese hemodialysis patients., PMID:40441692
Crystal-Storing Histiocytosis of the Duodenum in a Patient With IgG-Lambda Multiple Myeloma., PMID:40440188
B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements., PMID:40402557
Increasing the developability of lambda chain antibodies: engineering to confer protein L binding activity and its consequences., PMID:40368210
Using bispecific antibodies in a patient with peritoneal dialysis for relapsed multiple myeloma., PMID:40356496
[Application of next-generation sequencing technology for the investigation of immunoglobulin variable region characteristics and their prognostic significance in patients with chronic lymphocytic leukemia]., PMID:40355356
Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells., PMID:40330075
[Localized AL amyloidosis]., PMID:40327620
Proliferative glomerulonephritis with monoclonal immunoglobulin deposition coexisting with ANCA-associated glomerulonephritis: a case report., PMID:40308572
Investigating Local Sequence-Structural Attributes of Amyloidogenic Light Chain Variable Domains., PMID:40034034
A case of IgG-type heavy chain amyloidosis with membranous nephropathy-like changes with long-term survival., PMID:40021557
Prevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy., PMID:39968567
[Construction and identification of a sizeable naive human Fab phage display antibody library]., PMID:39965836
[Assessment of serum free light chains in patients with systemic lupus erythematosus]., PMID:39960251
Extramedullary plasmacytoma with the uvula as first affected site: A case report., PMID:39867735
Biomarkers of Intrathecal Synthesis May Be Associated with Cognitive Impairment at MS Diagnosis., PMID:39859538
Comprehensive analysis of gene expressions in ileal mucosa of chickens fed paddy rice and their IgA response to oral vaccination., PMID:39848208
Diagnostic d'un myélome multiple à immunoglobuline D Lambda avec une atteinte rénale sévère 10 ans après un plasmocytome solitaire : Un cas clinique et revue de la littérature., PMID:39812210
Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chain., PMID:39758990
50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations., PMID:39727482
EXPRESSION OF IMMUNOGLOBULIN LIGHT CHAIN GENES IN STEREOTYPED CASES FROM UKRAINIAN COHORT OF CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS., PMID:39704461
[IgA vasculitis with necrosis of the small intestine secondary to monoclonal gammopathy of renal significance: A case report]., PMID:39690777
Single-cell analysis of a bi-clonal chronic lymphocytic leukemia reveals two clones with distinct gene expression pattern., PMID:39689719
An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis., PMID:39641756
Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains., PMID:39626211
Correlation analysis of laboratory indicators, genetic abnormalities and staging in patients with newly diagnosed multiple myeloma., PMID:39612380
Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis., PMID:39598451
Hybrid Mass Spectrometry Applied across the Production of Antibody Biotherapeutics., PMID:39573914
Serum free light chains in a racially diverse population including African Americans and populations from South Africa., PMID:39571144
[Free Immunoglobulin Light Chains in Patients With Myocarditis: a New Biomarker of Inflammation and Heart Failure]., PMID:39526514
Serum levels of free light chains and syndecan-1 in patients with rheumatoid arthritis and systemic lupus erythematosus., PMID:39509329
Monoclonal Gammopathy in Patients with Neuropathy., PMID:39506578
IgA monoclonal gammopathies are accompanied by higher total TGF-β1 levels than IgG or IgM monoclonal gammopathies., PMID:39506190
A clinical case of B-cell lymphoma in a Japanese Black cow with monoclonal proliferation of B-cells as revealed by polymerase chain reaction based on the immunoglobulin light chain gene., PMID:39496453
Warning values of serum total kappa/lambda ratio for M-proteinemia., PMID:39478462
Clonality Determination by Detecting Unmodified Monoclonal Serum Free Light Chains Using On-Probe Extraction Coupled with Liquid Chromatography-High-Resolution Mass Spectrometry., PMID:39378225
Lambda light chain - restricted non - crystalline proximal tubulopathy with cast nephropathy in multiple myeloma: a case report and literature review., PMID:39350086
An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis., PMID:39314448
Expression and diagnostic value of serum free light chain in lung cancer., PMID:39311787
Biochemical profile of renal amyloidosis in a Latin American cohort., PMID:39225979
Optimizing the method for expressing human monoclonal antibodies from a single peripheral blood cell from vaccinated donors., PMID:39214236
Features that characterize monoclonal light chain ("myeloma") cast nephropathy with immunofluorescence challenges and emphasis on electron microscopy., PMID:39166773
Failure of Serum Immunofixation Electrophoresis to Detect Intact Monoclonal IgD Lambda Unraveled by Mass Spectrometry., PMID:39162305
Detecting M-Protein via Mass Spectrometry and Affinity Beads: Enrichment With Mixed Kappa-Lambda Beads Enables Prompt Application in Clinical Laboratories., PMID:39161319
Generation of Chicken Antibody Libraries and Selection of Antigen Binders., PMID:39151941
Generation of a Phage Display Chicken Single-Chain Variable Fragment Library., PMID:39151940
Chicken Immunization followed by RNA Extraction and cDNA Synthesis for Antibody Library Preparation., PMID:39151937
Promising response of proliferative glomerulonephritis with monoclonal IgG deposits to low-dose daratumumab: a case report., PMID:39114824
For research use only. Not for human or drug use.
