Catalog No.
PHN50201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IRGM (Met1-Tyr181).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Immunity-related GTPase family M protein, 3.6.5.-, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47, IRGM, IFI1, IRGM1, LRG47
Purification
Purified by antigen affinity column.
Accession
A1A4Y4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Novel Targets for the Development of Tuberculosis Vaccine., PMID:38859789
Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion., PMID:37874678
Analysis of rs1864182 and rs1864183 variants in ATG10 gene and antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese Guangxi population., PMID:34961976
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn's disease., PMID:29434451
Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease., PMID:29228965
HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)., PMID:25484075
A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene., PMID:25369137
Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease., PMID:22275320
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Interactions between the host innate immune system and microbes in inflammatory bowel disease., PMID:21530739
Ginsenoside Re enhances survival of human CD4+ T cells through regulation of autophagy., PMID:20230918