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Anti-Human IRGM Polyclonal Antibody

Catalog #:   PHN50201 Specific References (12) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: A1A4Y4
Overview

Catalog No.

PHN50201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IRGM (Met1-Tyr181).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Immunity-related GTPase family M protein, 3.6.5.-, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47, IRGM, IFI1, IRGM1, LRG47

Purification

Purified by antigen affinity column.

Accession

A1A4Y4

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IRGM antibody (PHN50201) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Novel Targets for the Development of Tuberculosis Vaccine., PMID:38859789

Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion., PMID:37874678

Analysis of rs1864182 and rs1864183 variants in ATG10 gene and antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese Guangxi population., PMID:34961976

Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392

Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn's disease., PMID:29434451

Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease., PMID:29228965

HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)., PMID:25484075

A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene., PMID:25369137

Pattern recognition receptor and autophagy gene variants are associated with development of antimicrobial antibodies in Crohn's disease., PMID:22275320

Innate immunity in the small intestine., PMID:22241076

Interactions between the host innate immune system and microbes in inflammatory bowel disease., PMID:21530739

Ginsenoside Re enhances survival of human CD4+ T cells through regulation of autophagy., PMID:20230918

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human IRGM Polyclonal Antibody [PHN50201]
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