Catalog No.
PHN16001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ERBIN (Lys1319-Val1407).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Erbin, Densin-180-like protein, Erbb2-interacting protein, Protein LAP2, ERBIN, ERBB2IP, KIAA1225, LAP2
Purification
Purified by antigen affinity column.
Accession
Q96RT1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
From phenotypic to molecular diagnosis: Insights from a clinical immunology service focused on inborn errors of immunity in Colombia., PMID:39836844
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Crohn's Disease and Early Exposure to Thiopurines are Independent Risk Factors for Mosaic Chromosomal Alterations in Patients with Inflammatory Bowel Diseases., PMID:34751398
Sorting of cadherin-catenin-associated proteins into individual clusters., PMID:34272290
Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer., PMID:33707428
An Update on Syndromes with a Hyper-IgE Phenotype., PMID:30466772
ERBB2 oncogenicity: ERBIN helps to perform the job., PMID:27308480
Downregulation of Erbin in Her2-overexpressing breast cancer cells promotes cell migration and induces trastuzumab resistance., PMID:23711387
A monoclonal antibody toolkit for C. elegans., PMID:20405020
Proteomic analysis of a PDEF Ets transcription factor-interacting protein complex., PMID:19203193
Overexpression, refolding, purification of Erbin PDZ domain from Escherichia coli and preparation of its polyclonal antibody., PMID:18569875
Quantitative characterization of the large-scale association of ErbB1 and ErbB2 by flow cytometric homo-FRET measurements., PMID:18487307
EGFR and ErbB2 are functionally coupled to CD44 and regulate shedding, internalization and motogenic effect of CD44., PMID:18276068
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition., PMID:17457301
Erbin enhances voltage-dependent facilitation of Ca(v)1.3 Ca2+ channels through relief of an autoinhibitory domain in the Ca(v)1.3 alpha1 subunit., PMID:17287512
Role for erbin in bacterial activation of Nod2., PMID:16714539
Herceptin and the heart--a molecular modifier of cardiac failure., PMID:16495390
Comparative analysis of the expression of ERBIN and Erb-B2 in normal human skin and cutaneous carcinomas., PMID:15948989
Basolateral targeting of ERBB2 is dependent on a novel bipartite juxtamembrane sorting signal but independent of the C-terminal ERBIN-binding domain., PMID:12192053
The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression., PMID:11375975
ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor., PMID:10878805