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Anti-Human KLK11 Polyclonal Antibody

Catalog #:   PHJ74101 Specific References (45) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9UBX7
Overview

Catalog No.

PHJ74101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KLK11 (Ile54-Asn282).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Kallikrein-11, hK11, 3.4.21.-, Hippostasin, Serine protease 20, Trypsin-like protease, Kallikrein-11 inactive chain 1, Kallikrein-11 inactive chain 2, KLK11, PRSS20, TLSP, UNQ649/PRO1279

Purification

Purified by antigen affinity column.

Accession

Q9UBX7

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with KLK11 antibody (PHJ74101) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 28 kDa
    Observed MW: 28 kDa
References

Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge., PMID:33353951

Development of a specific immunoassay to selectively measure active tryptase in airway samples., PMID:32975431

Elevated plasma endocan and BOC in heart failure patients decrease after heart transplantation in association with improved hemodynamics., PMID:32651845

Molecular characterization of a 31 kDa protein from Trichinella spiralis and its induced immune protection in BALB/c mice., PMID:30518426

Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients., PMID:30323977

Characterization of an antigenic serine protease in the Trichinella spiralis adult., PMID:30248330

Two B-cell epitope vaccines based on uPA effectively inhibit fertility in male mice., PMID:29631885

Ligand binding modulates the structural dynamics and activity of urokinase-type plasminogen activator: A possible mechanism of plasminogen activation., PMID:29420634

Histones and chymotrypsin-like elastases play significant roles in the antimicrobial activity of tongue sole neutrophil extracellular traps., PMID:29117594

Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator., PMID:28611361

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity., PMID:26513360

Induction of proteinase 3-anti-neutrophil cytoplasmic autoantibodies by proteinase 3-homologous bacterial protease in mice., PMID:26318749

Selection and characterization of camelid nanobodies towards urokinase-type plasminogen activator., PMID:25749705

PmPPAF is a pro-phenoloxidase activating factor involved in innate immunity response of the shrimp Penaeus monodon., PMID:24345607

Is human kallikrein-11 in gastric cancer treated with surgery and adjuvant chemoradiotherapy associated with survival?, PMID:24169449

Allosteric inactivation of a trypsin-like serine protease by an antibody binding to the 37- and 70-loops., PMID:24079451

Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome., PMID:23086370

Granzyme K activates protease-activated receptor-1., PMID:21760880

Matrix remodeling as stem cell recruitment event: a novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix., PMID:20828613

Trypsin-like serine proteases in Lutzomyia longipalpis--expression, activity and possible modulation by Leishmania infantum chagasi., PMID:20502532

Unraveling the allosteric mechanism of serine protease inhibition by an antibody., PMID:20004165

Identification of a serine protease as a major allergen (Per a 10) of Periplaneta americana., PMID:18445191

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library., PMID:17662146

Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients., PMID:17518992

Characterization of a shrimp serine protease homolog, a binding protein of yellow head virus., PMID:17451807

Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma., PMID:16467084

Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells., PMID:15557757

Immunolocalization of bovine sperm protease BSp120 by light and electron microscopy during capacitation and the acrosome reaction: its role in in vitro fertilization., PMID:15457518

Serine proteases in the spiny lobster olfactory organ: their functional expression along a developmental axis, and the contribution of a CUB-serine protease., PMID:15389692

Partial purification and characterization of a trypsin-like serine protease from bovine sperm., PMID:15379973

A novel serine protease predominately expressed in macrophages., PMID:12795636

Low temperature-induced dimerization of the bovine sperm serine protease, BSp66., PMID:12616542

Characterization of a brain-related serine protease, neurosin (human kaillikrein 6), in human cerebrospinal fluid., PMID:11388408

Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor., PMID:11231297

Localization of the mosaic transmembrane serine protease corin to heart myocytes., PMID:11082206

Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease., PMID:10997858

Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation., PMID:10514489

Regulation of the catalytic function of coagulation factor VIIa by a conformational linkage of surface residue Glu 154 to the active site., PMID:10052945

Recombinant human mast cell tryptase beta: stable expression in Pichia pastoris and purification of fully active enzyme., PMID:9756742

Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa., PMID:9545384

Molecular basis of proteolytic activation of Sendai virus infection and the defensive compounds for infection., PMID:9165079

Cellular mechanisms of estrogen- and dopamine-induced control of glandular kallikrein in the anterior pituitary of the rat., PMID:7507405

Expression and utilization of chymotrypsin-like but not trypsin-like serine protease enzymes by nonspecific T killer cells activated by anti-CD3 monoclonal antibody., PMID:1532539

Modulation of type II Fc gamma receptor expression on activated human B lymphocytes., PMID:1826259

An estrogen-stimulated, calcium-dependent tosylarginine methyl ester (TAME) hydrolase in immature rat uterus., PMID:6357893

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human KLK11 Polyclonal Antibody [PHJ74101]
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