Catalog No.
PHD98501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ARRB2 (Met1-Pro368).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Beta-arrestin-2, Arrestin beta-2, Non-visual arrestin-3, ARRB2, ARB2, ARR2
Purification
Purified by antigen affinity column.
Accession
P32121
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
LuQi formula ameliorates pressure overload-induced heart failure by regulating macrophages and regulatory T cells., PMID:40118747
Mast cell MrgprB2 in neuroimmune interaction in IgE-mediated airway inflammation and its modulation by β-arrestin2., PMID:39483467
β-arrestin2 deficiency ameliorates S-100-induced autoimmune hepatitis in mice by inhibiting infiltration of monocyte-derived macrophage and attenuating hepatocyte apoptosis., PMID:37225848
A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation., PMID:36399825
SR-17018 Stimulates Atypical µ-Opioid Receptor Phosphorylation and Dephosphorylation., PMID:34361663
Proteome profiling reveals the efficacy and targets of sophocarpine against asthma., PMID:33857804
Anti-ATR001 monoclonal antibody ameliorates atherosclerosis through beta-arrestin2 pathway., PMID:33516876
Deficiency of β-arrestin2 exacerbates inflammatory arthritis by facilitating plasma cell formation., PMID:32855529
Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide., PMID:32579945
Arrestin-β-1 Physically Scaffolds TSH and IGF1 Receptors to Enable Crosstalk., PMID:31127272
β-Arrestin2 expressed in mast cells regulates ciprofloxacin-induced pseudoallergy and IgE-mediated anaphylaxis., PMID:31077686
Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody From Preeclampsia., PMID:30845870
Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells., PMID:27657826
Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers., PMID:26372541
β-Arrestin2 encourages inflammation-induced epithelial apoptosis through ER stress/PUMA in colitis., PMID:25354317
Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide., PMID:25318610
Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity., PMID:24657625
Enhancement of morphine analgesia and prevention of morphine tolerance by downregulation of β-arrestin 2 with antigene RNAs in mice., PMID:24555516
Antidepressant-induced differential ubiquitination of β-arrestins 1 and 2 in mononuclear leucocytes of patients with depression., PMID:23672745
CXCR7 mediates SDF1-induced melanocyte migration., PMID:22978759
G protein-coupled receptor kinase 2, with β-arrestin 2, impairs insulin-induced Akt/endothelial nitric oxide synthase signaling in ob/ob mouse aorta., PMID:22688330
Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation., PMID:21855149
Screening and identification of host factors interacting with UL14 of herpes simplex virus 1., PMID:21512757
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)., PMID:20686112
Fenoterol, a beta(2)-adrenoceptor agonist, inhibits LPS-induced membrane-bound CD14, TLR4/CD14 complex, and inflammatory cytokines production through beta-arrestin-2 in THP-1 cell line., PMID:19890360
Hematopoietic protein tyrosine phosphatase mediates beta2-adrenergic receptor-induced regulation of p38 mitogen-activated protein kinase in B lymphocytes., PMID:19047375
Beta2-adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-kappaB activation through beta-arrestin 2., PMID:18194271
RGS9-2 is a negative modulator of mu-opioid receptor function., PMID:17725581
Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies., PMID:17329249
Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization., PMID:16497811
Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation., PMID:16407241
Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor., PMID:16183993
Beta-arrestin-2 regulates the development of allergic asthma., PMID:12925697
Involvement of beta-arrestin-2 in modulation of the spinal antinociception induced by mu-opioid receptor agonists in the mouse., PMID:12850536
Regulation of GRK 2 and 6, beta-arrestin-2 and associated proteins in the prefrontal cortex of drug-free and antidepressant drug-treated subjects with major depression., PMID:12654503
Parathyroid hormone receptor recycling: role of receptor dephosphorylation and beta-arrestin., PMID:12456793
G protein-coupled receptor kinases, beta-arrestin-2 and associated regulatory proteins in the human brain: postmortem changes, effect of age and subcellular distribution., PMID:12007830
Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization., PMID:8381559
For research use only. Not for human or drug use.
