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Anti-Human SLC6A1 Polyclonal Antibody

Catalog #:   PHD89601 Specific References (37) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P30531
Overview

Catalog No.

PHD89601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC6A1 (Ser145-Arg211).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1, SLC6A1, GABATR, GABT1, GAT1

Purification

Purified by antigen affinity column.

Accession

P30531

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with SLC6A1 antibody (PHD89601) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 24 kDa
    Observed MW: 24 kDa
References

Analysis of Significant Genes and Pathways in Esophageal Cancer Based on Gene Expression Omnibus Database., PMID:36855320

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse., PMID:35551574

α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia., PMID:33111258

Ontogenetic changes in the distribution of the vesicular GABA transporter VGAT correlate with the excitation/inhibition shift of GABA action., PMID:22490609

Effect of early glutamate exposure on EAAT-3 and GAT-1 protein expression in cells of the dentate gyrus and CA1 region of the adult rat hippocampus., PMID:21924306

Raphe serotonin neurons are not homogenous: electrophysiological, morphological and neurochemical evidence., PMID:21530552

Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: effects on proactive interference., PMID:20865731

Plasmalemmal and vesicular gamma-aminobutyric acid transporter expression in the developing mouse retina., PMID:18975268

A screen for neurotransmitter transporters expressed in the visual system of Drosophila melanogaster identifies three novel genes., PMID:17443808

Expression of the gamma-aminobutyric acid (GABA) plasma membrane transporter-1 in monkey and human retina., PMID:16565409

Expression of GABA transporters, GAT-1 and GAT-3, in the cerebral cortex and thalamus of the rat during postnatal development., PMID:12898208

Altered gene expression in frontal cortex and midbrain of 3,4-methylenedioxymethamphetamine (MDMA) treated mice: differential regulation of GABA transporter subtypes., PMID:12672000

Neuronal and glial localization of GABA transporter immunoreactivity in the myenteric plexus., PMID:12107427

Gamma-aminobutyric acid transporter (GAT1) overexpression in mouse affects the testicular morphology., PMID:10765984

A light and electron microscopic study of GAT-1-positive cells in the cerebral cortex of man and monkey., PMID:10640187

GAT-1 developmental expression in the rat cerebellar cortex: basket and pinceau formation., PMID:10094127

Developmental expression of gamma-aminobutyric acid transporters (GAT-1 and GAT-3) in the rat cerebellum: evidence for a transient presence of GAT-1 in Purkinje cells., PMID:9838150

GABA and GABA-transporter (GAT-1) immunoreactivities in the retina of the salmon (Salmo salar L.)., PMID:9813314

Reduction of GABA and glutamate transporter messenger RNAs in the severe-seizure genetically epilepsy-prone rat., PMID:9681960

Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex., PMID:9623887

A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia., PMID:9560277

Immunocytochemical localization of gamma-aminobutyric acid plasma membrane transporters in the tiger salamander retina., PMID:9390763

Sorting of two polytopic proteins, the gamma-aminobutyric acid and betaine transporters, in polarized epithelial cells., PMID:9045687

Neuronal and glial localization of the GABA transporter GAT-1 in the cerebellar cortex., PMID:9116226

Multiple gamma-Aminobutyric acid plasma membrane transporters (GAT-1, GAT-2, GAT-3) in the rat retina., PMID:8915826

Astrocytic processes compensate for the apparent lack of GABA transporters in the axon terminals of cerebellar Purkinje cells., PMID:8896702

GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex., PMID:8815906

Developmental expression of GABA transporters GAT1 and GAT4 suggests involvement in brain maturation., PMID:8764616

GABA plasma membrane transporters, GAT-1 and GAT-3, display different distributions in the rat hippocampus., PMID:8731228

Neuronal and glial localization of two GABA transporters (GAT1 and GAT3) in the rat cerebellum., PMID:8738166

Immunocytochemical localization of three subtypes of GABA transporter in rat retina., PMID:8750892

GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex., PMID:7472524

Localization of messenger RNAs encoding three GABA transporters in rat brain: an in situ hybridization study., PMID:8774941

Localization of GAT-1 GABA transporter mRNA in rat striatum: cellular coexpression with GAD67 mRNA, GAD67 immunoreactivity, and parvalbumin mRNA., PMID:7823186

Structure, function and brain localization of neurotransmitter transporters., PMID:7823028

Production of specific antibodies against GABA transporter subtypes (GAT1, GAT2, GAT3) and their application to immunocytochemistry., PMID:7854065

Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells., PMID:1536839

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human SLC6A1 Polyclonal Antibody [PHD89601]
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