Catalog No.
PHD60901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PRPH2 (Arg123-Gly208).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Peripherin-2, Retinal degeneration slow protein, Tetraspanin-22, Tspan-22, PRPH2, PRPH, RDS, TSPAN22
Purification
Purified by antigen affinity column.
Accession
P23942
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Choroidal neovascularization associated with butterfly-shaped pattern dystrophy - a case report., PMID:37522013
PRPF31 interacts with PRPH2 confirmed by co-immunoprecipitation and co-localization., PMID:36088804
Treatment and longitudinal follow-up of CNV associated with pattern dystrophy with novel PRPH2 variant., PMID:34486473
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition., PMID:34132745
OCT-angiography assessing quiescent and active choroidal neovascularization in retinitis pigmentosa associated with PRPH2 pathogenic variant., PMID:33736480
Long-term efficacy and safety of anti-VEGF therapy in retinitis pigmentosa: a case report., PMID:30217183
Pattern dystrophy with high intrafamilial variability associated with Y141C mutation in the peripherin/RDS gene and successful treatment of subfoveal CNV related to multifocal pattern type with anti-VEGF (ranibizumab) intravitreal injections., PMID:22466463
Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression., PMID:21774040
A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression., PMID:20447394
Clinicopathological case series of four patients with inherited macular disease., PMID:19279306
Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation., PMID:18055786
The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator., PMID:17260955
Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals., PMID:16639027
Expression of aquaporin-1 immunoreactivity by photoreceptor cells in the mouse retina., PMID:16039047
Modulating expression of peripherin/rds in transgenic mice: critical levels and the effect of overexpression., PMID:15277471
Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects., PMID:15252042
A soluble peripherin/Rds C-terminal polypeptide promotes membrane fusion and changes conformation upon membrane association., PMID:12957149
Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal region., PMID:12137760
Investigating the mechanisms of retinal degenerations with antisense oligonucleotides., PMID:11556485
Expression and characterization of peripherin/rds-rom-1 complexes and mutants implicated in retinal degenerative diseases., PMID:10800708
Characterization of antibody against the N-terminus of RDS/peripherin., PMID:9810572
Molecular cloning, membrane topology, and localization of bovine rom-1 in rod and cone photoreceptor cells., PMID:8603840
[A molecular biological study on retinitis pigmentosa]., PMID:7904791
[Molecular cloning of the genes in genetic chorioretinal diseases--positional cloning and the candidate gene approach]., PMID:8285146
Localization of peripherin/rds in the disk membranes of cone and rod photoreceptors: relationship to disk membrane morphogenesis and retinal degeneration., PMID:1730772
Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse., PMID:1992463
For research use only. Not for human or drug use.
