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Anti-Human MCC Polyclonal Antibody

Catalog #:   PHD58702 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P23508
Overview

Catalog No.

PHD58702

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MCC (Ser342-Leu588).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Colorectal mutant cancer protein, Protein MCC, MCC

Purification

Purified by antigen affinity column.

Accession

P23508

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MCC antibody (PHD58702) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 29 kDa
    Observed MW: 29 kDa
References

RLEAAI: improving antibody-antigen interaction prediction using protein language model and sequence order information., PMID:40462512

Evaluation of Baseline Characteristics and Therapeutic Management Strategies in Metastatic Cervical Cancer in Germany: A Multicentric Retrospective Longitudinal Observational Study: A Quality Assurance Initiative of the AGO-Study Group and AGO-OK Uterus., PMID:40386500

m276-SL-PBD eradicates tumors and instigates long-lasting tumor-free survival in Merkel cell carcinoma preclinical models., PMID:40384933

Development and validation of a multiple myeloma diagnostic model based on systemic lupus erythematosus-associated genes and identification of specific genes., PMID:40382732

Development and Characterization of a Primary Ciliated Porcine Airway Model for the Evaluation of In Vitro Mucociliary Clearance and Mucosal Drug Delivery., PMID:40284456

Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide-HLA-I Fusion Protein by Armoring with Mutein IFNα., PMID:40243928

Seroprevalence of Enterovirus 71 Among Children in Western India., PMID:40143284

Probiotic characterization, safety assessment, and production performance of a novel probiotic strain of Bacillus subtilis SKB/2074 (MCC 0563) in broiler chickens., PMID:40122117

Safety, tolerability and immunogenicity of a condensed, multi-dose prime regimen of PfSPZ Vaccine for the prevention of Plasmodium falciparum malaria infection., PMID:40098097

Optimization of Adcitmer, a Monomethyl-Auristatin E bearing antibody-drug conjugate for the treatment of CD56-expressing cancers., PMID:40086820

A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills., PMID:40007443

Merkel Cell Polyomavirus Co-Infection in HIV/AIDS Individuals: Clinical Diagnosis, Consequences and Treatments., PMID:40005510

Clinical implications of proximal tubular multicilia in glomerular diseases., PMID:39991237

Operationalizing selection criteria for clinical trials in Alzheimer's disease: Biomarker and clinical considerations: Proceedings from the Alzheimer's Association Research Roundtable (AARR) Fall 2021 meeting., PMID:39935618

Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study., PMID:39889250

Clinical outcomes and management following progressive disease with anti-PD-(L)1 therapy in patients with advanced Merkel Cell Carcinoma., PMID:39874912

An Immunocytochemistry Method to Investigate the Translationally Active HIV Reservoir., PMID:39859395

Evaluating CK20 and MCPyV Antibody Clones in Diagnosing Merkel Cell Carcinoma., PMID:39841326

Nicotinic Acetylcholine Receptor Expression in Merkel Cell Carcinoma Is Associated With Clinical and Histopathologic Parameters., PMID:39814046

Quality by Design in continuous bioprocessing: Investigating the impact of critical process parameters of multi-column chromatography during steady-state and transient phases., PMID:39755054

Re-exposition to ipilimumab plus nivolumab in metastatic Merkel cell carcinoma., PMID:39703511

Use of osteogenic bone matrix in patients with traumatic long bone defects: An open label, single center study., PMID:39678257

ParaAntiProt provides paratope prediction using antibody and protein language models., PMID:39587231

Association of Pulmonary Hypertension With Trastuzumab Emtansine: An Analysis of French Pulmonary Hypertension Registry and WHO Pharmacovigilance Database., PMID:39571726

Streamlined Clarification and Capture Process for Monoclonal Antibodies Using Fluidized Bed Centrifugation and Multi-Column Chromatography With Membrane Adsorbers., PMID:39558619

Defining Objective BASDAI Cut-Offs for Disease Activity States and Improvement Scores in Axial Spondyloarthritis: A Multicentric Collaboration., PMID:39555624

Ab-Amy 2.0: Predicting light chain amyloidogenic risk of therapeutic antibodies based on antibody language model., PMID:39550021

Serum antibodies against mimotopes of Merkel cell polyomavirus oncoproteins detected by a novel immunoassay in healthy individuals and Merkel cell carcinoma patients., PMID:39460382

Modeling and techno-economic analysis of downstream manufacturing process intensification strategies for existing biopharmaceutical facilities., PMID:39454502

Targeting the TNF and TNFR superfamilies in autoimmune disease and cancer., PMID:39448880

Phase II study of enlonstobart (SG001), a novel PD-1 inhibitor in patients with PD-L1 positive recurrent/metastatic cervical cancer., PMID:39447517

Safety and efficacy of tisotumab vedotin with cervical cancers: A systematic review and meta-analysis., PMID:39428336

Neoadjuvant Intratumoral Plasmid IL-12 Electro-Gene-Transfer and Nivolumab in Patients with Operable, Locoregionally Advanced Melanoma., PMID:39417680

Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling., PMID:39410666

Intratumoral STING agonist reverses immune evasion in PD-(L)1-refractory Merkel cell carcinoma: mechanistic insights from detailed biomarker analyses., PMID:39401968

[Translated article] Avelumab to treat Merkel cell carcinoma: real-life experience in a dedicated oncology center., PMID:39395689

Paraneoplastic Neurologic Syndromes Associated With Merkel Cell Carcinoma., PMID:39388653

Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study., PMID:39377880

Merkel Cell Polyomavirus Antibody in Tumor and Plasma Specimens in Patients with Merkel Cell Carcinoma., PMID:39373930

Clinical Meaningfulness in Alzheimer's Disease Clinical Trials. A Report from the EU-US CTAD Task Force., PMID:39350367

Antibody drug conjugates in recurrent or metastatic cervical cancer: a focus on tisotumab vedotin state of art., PMID:39323928

Benefits and risks of FDA-approved amyloid-targeting antibodies for treatment of early Alzheimer's disease: Navigating clinician-patient engagement., PMID:39306695

Hydrophobic interaction chromatography in continuous flow-through mode for product-related variant removal., PMID:39276416

Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial., PMID:39236736

Development of a Multiplex Immunofluorescence Assay for Tumor Microenvironment Studies of Human and Murine Merkel Cell Carcinoma., PMID:39182611

Polyphenol-Enabled 2D Nanopatch for Enhanced Nasal Mucoadhesion and Immune Activation., PMID:39120059

Changes in Merkel cell oncoprotein antibodies after radiation therapy in curatively treated Merkel cell carcinoma and association with recurrence., PMID:39101686

Profound ctDNA and radiological responses after 2 cycles of avelumab in a metastatic Merkel cell carcinoma of the head and neck., PMID:39067262

Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study., PMID:39054467

Merkel cell carcinoma refractory to anti-PD(L)1: utility of adding ipilimumab for salvage therapy., PMID:39053946

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human MCC Polyclonal Antibody [PHD58702]
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