RLEAAI: improving antibody-antigen interaction prediction using protein language model and sequence order information., PMID:40462512
Evaluation of Baseline Characteristics and Therapeutic Management Strategies in Metastatic Cervical Cancer in Germany: A Multicentric Retrospective Longitudinal Observational Study: A Quality Assurance Initiative of the AGO-Study Group and AGO-OK Uterus., PMID:40386500
m276-SL-PBD eradicates tumors and instigates long-lasting tumor-free survival in Merkel cell carcinoma preclinical models., PMID:40384933
Development and validation of a multiple myeloma diagnostic model based on systemic lupus erythematosus-associated genes and identification of specific genes., PMID:40382732
Development and Characterization of a Primary Ciliated Porcine Airway Model for the Evaluation of In Vitro Mucociliary Clearance and Mucosal Drug Delivery., PMID:40284456
Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide-HLA-I Fusion Protein by Armoring with Mutein IFNα., PMID:40243928
Seroprevalence of Enterovirus 71 Among Children in Western India., PMID:40143284
Probiotic characterization, safety assessment, and production performance of a novel probiotic strain of Bacillus subtilis SKB/2074 (MCC 0563) in broiler chickens., PMID:40122117
Safety, tolerability and immunogenicity of a condensed, multi-dose prime regimen of PfSPZ Vaccine for the prevention of Plasmodium falciparum malaria infection., PMID:40098097
Optimization of Adcitmer, a Monomethyl-Auristatin E bearing antibody-drug conjugate for the treatment of CD56-expressing cancers., PMID:40086820
A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills., PMID:40007443
Merkel Cell Polyomavirus Co-Infection in HIV/AIDS Individuals: Clinical Diagnosis, Consequences and Treatments., PMID:40005510
Clinical implications of proximal tubular multicilia in glomerular diseases., PMID:39991237
Operationalizing selection criteria for clinical trials in Alzheimer's disease: Biomarker and clinical considerations: Proceedings from the Alzheimer's Association Research Roundtable (AARR) Fall 2021 meeting., PMID:39935618
Nivolumab With or Without Ipilimumab in Patients With Recurrent or Metastatic Merkel Cell Carcinoma: A Nonrandomized, Open-Label, International, Multicenter Phase I/II Study., PMID:39889250
Clinical outcomes and management following progressive disease with anti-PD-(L)1 therapy in patients with advanced Merkel Cell Carcinoma., PMID:39874912
An Immunocytochemistry Method to Investigate the Translationally Active HIV Reservoir., PMID:39859395
Evaluating CK20 and MCPyV Antibody Clones in Diagnosing Merkel Cell Carcinoma., PMID:39841326
Nicotinic Acetylcholine Receptor Expression in Merkel Cell Carcinoma Is Associated With Clinical and Histopathologic Parameters., PMID:39814046
Quality by Design in continuous bioprocessing: Investigating the impact of critical process parameters of multi-column chromatography during steady-state and transient phases., PMID:39755054
Re-exposition to ipilimumab plus nivolumab in metastatic Merkel cell carcinoma., PMID:39703511
Use of osteogenic bone matrix in patients with traumatic long bone defects: An open label, single center study., PMID:39678257
ParaAntiProt provides paratope prediction using antibody and protein language models., PMID:39587231
Association of Pulmonary Hypertension With Trastuzumab Emtansine: An Analysis of French Pulmonary Hypertension Registry and WHO Pharmacovigilance Database., PMID:39571726
Streamlined Clarification and Capture Process for Monoclonal Antibodies Using Fluidized Bed Centrifugation and Multi-Column Chromatography With Membrane Adsorbers., PMID:39558619
Defining Objective BASDAI Cut-Offs for Disease Activity States and Improvement Scores in Axial Spondyloarthritis: A Multicentric Collaboration., PMID:39555624
Ab-Amy 2.0: Predicting light chain amyloidogenic risk of therapeutic antibodies based on antibody language model., PMID:39550021
Serum antibodies against mimotopes of Merkel cell polyomavirus oncoproteins detected by a novel immunoassay in healthy individuals and Merkel cell carcinoma patients., PMID:39460382
Modeling and techno-economic analysis of downstream manufacturing process intensification strategies for existing biopharmaceutical facilities., PMID:39454502
Targeting the TNF and TNFR superfamilies in autoimmune disease and cancer., PMID:39448880
Phase II study of enlonstobart (SG001), a novel PD-1 inhibitor in patients with PD-L1 positive recurrent/metastatic cervical cancer., PMID:39447517
Safety and efficacy of tisotumab vedotin with cervical cancers: A systematic review and meta-analysis., PMID:39428336
Neoadjuvant Intratumoral Plasmid IL-12 Electro-Gene-Transfer and Nivolumab in Patients with Operable, Locoregionally Advanced Melanoma., PMID:39417680
Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling., PMID:39410666
Intratumoral STING agonist reverses immune evasion in PD-(L)1-refractory Merkel cell carcinoma: mechanistic insights from detailed biomarker analyses., PMID:39401968
[Translated article] Avelumab to treat Merkel cell carcinoma: real-life experience in a dedicated oncology center., PMID:39395689
Paraneoplastic Neurologic Syndromes Associated With Merkel Cell Carcinoma., PMID:39388653
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study., PMID:39377880
Merkel Cell Polyomavirus Antibody in Tumor and Plasma Specimens in Patients with Merkel Cell Carcinoma., PMID:39373930
Clinical Meaningfulness in Alzheimer's Disease Clinical Trials. A Report from the EU-US CTAD Task Force., PMID:39350367
Antibody drug conjugates in recurrent or metastatic cervical cancer: a focus on tisotumab vedotin state of art., PMID:39323928
Benefits and risks of FDA-approved amyloid-targeting antibodies for treatment of early Alzheimer's disease: Navigating clinician-patient engagement., PMID:39306695
Hydrophobic interaction chromatography in continuous flow-through mode for product-related variant removal., PMID:39276416
Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial., PMID:39236736
Development of a Multiplex Immunofluorescence Assay for Tumor Microenvironment Studies of Human and Murine Merkel Cell Carcinoma., PMID:39182611
Polyphenol-Enabled 2D Nanopatch for Enhanced Nasal Mucoadhesion and Immune Activation., PMID:39120059
Changes in Merkel cell oncoprotein antibodies after radiation therapy in curatively treated Merkel cell carcinoma and association with recurrence., PMID:39101686
Profound ctDNA and radiological responses after 2 cycles of avelumab in a metastatic Merkel cell carcinoma of the head and neck., PMID:39067262
Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study., PMID:39054467
Merkel cell carcinoma refractory to anti-PD(L)1: utility of adding ipilimumab for salvage therapy., PMID:39053946