Catalog No.
PHD41601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BCL3 (Ser122-Gly360).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
BCL-3, B-cell lymphoma 3 protein, Proto-oncogene BCL3, BCL4, BCL3, D19S37
Purification
Purified by antigen affinity column.
Accession
P20749
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
BCL3 rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases., PMID:37560801
[Clinical analysis of 20 cases of small B lymphocyte proliferative disease with t (14;19) (q32;q13)]., PMID:36709153
Patterns of utilization and clinical adoption of 0.35 Tesla MR-guided radiation therapy in the United States - Understanding the transition to adaptive, ultra-hypofractionated treatments., PMID:36466748
Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure., PMID:35641486
Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia., PMID:34732719
TRPM2, PDLIM5, BCL3, CD14, GBA Genes as Feasible Markers for Premature Coronary Heart Disease Risk., PMID:34093636
Genetic Factors in Antiphospholipid Syndrome: Preliminary Experience with Whole Exome Sequencing., PMID:33333988
Expression of DOCK10.1 protein revealed with a specific antiserum: insights into regulation of first exon isoforms of DOCK10., PMID:32112301
RNA Sequencing (RNA-Seq) Based Transcriptome Analysis in Immune Response of Holstein Cattle to Killed Vaccine against Bovine Viral Diarrhea Virus Type I., PMID:32098229
Transcription Factor STAT3 Serves as a Negative Regulator Controlling IgE Class Switching in Mice., PMID:31026806
IGH translocations in chronic lymphocytic leukemia: Clinicopathologic features and clinical outcomes., PMID:30575108
The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells., PMID:30135206
Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation., PMID:29928964
EBV-positive nodal low-grade B-cell lymphoma with BCL3, IgA and IRTA1 expression: Is this a polymorphic lymphoproliferative disorder or an EBV-positive nodal marginal zone lymphoma?, PMID:29920862
Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner., PMID:28835002
Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency., PMID:28674400
Expression of Toll-like receptor signaling-related genes in pigs co-infected with porcine reproductive and respiratory syndrome virus and porcine circovirus type 2., PMID:26022073
Involvement of the NF-кB/p50/Bcl-3 complex in response to antiangiogenic therapy in a mouse model of metastatic renal cell carcinoma., PMID:25113400
Immunobiotic Lactobacillus jensenii as immune-health promoting factor to improve growth performance and productivity in post-weaning pigs., PMID:24943108
Alteration of energy metabolism in the pathogenesis of bile duct lesions in primary biliary cirrhosis., PMID:24293610
The tumor promoter and NF-κB modulator Bcl-3 regulates splenic B cell development., PMID:24244019
Bcl-3 suppresses Tax-induced NF-κB activation through p65 nuclear translocation blockage in HTLV-1-infected cells., PMID:23135533
Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein., PMID:22558084
Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis., PMID:20974684
MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate., PMID:20572854
BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1., PMID:20558726
Adiponectin inhibits pro-inflammatory signaling in human macrophages independent of interleukin-10., PMID:19617629
Expression of a B-cell-restricted isoform of CD45 is associated with maturity in rat serosal and connective-tissue mast cells., PMID:19137648
BCL2 and BCL3 are recurrent translocation partners of the IGH locus., PMID:18940474
Chronic lymphocytic leukemia FISH panel: impact on diagnosis., PMID:17638669
Tissue microarray-based screening for chromosomal breakpoints affecting the T-cell receptor gene loci in mature T-cell lymphomas., PMID:17582237
The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases., PMID:17129229
Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma., PMID:17079453
Reappraisal of BCL3 as a molecular marker of anaplastic large cell lymphoma., PMID:16533741
Splenic small B-cell lymphoma with IGH/BCL3 translocation., PMID:16426923
Interphase fluorescence in situ hybridization with an IGH probe is important in the evaluation of patients with a clinical diagnosis of chronic lymphocytic leukaemia., PMID:15982342
Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma., PMID:15481028
Immunohistochemical detection of BCL-3 in lymphoid neoplasms: a survey of 353 cases., PMID:15105810
Bcl-3/IgH translocation (14;19)(q32;q13) in non-Hodgkin's lymphomas., PMID:12153169
Activation of platelet caspases by TNF and its consequences for kinetics., PMID:12126645
Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3., PMID:12055593
The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia., PMID:12040429
Activation of an alternative NF-kappaB pathway in skeletal muscle during disuse atrophy., PMID:11919155
Interphase detection of immunoglobulin heavy chain gene translocations with specific oncogene loci in 173 patients with B-cell lymphoma., PMID:11520558
Vascular endothelial growth factor effects on nuclear factor-kappaB activation in hematopoietic progenitor cells., PMID:11280761
Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs., PMID:11278262
Nuclear factor-kappaB p50 is required for tumor necrosis factor-alpha-induced colony-stimulating factor-1 gene expression in osteoblasts., PMID:10919279
Distinct activities of p52/NF-kappa B required for proper secondary lymphoid organ microarchitecture: functions enhanced by Bcl-3., PMID:10586052
Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation., PMID:10497212