Catalog No.
PHC78801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAP2A (Met1-Gln183).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ras-related protein Rap-2a, 3.6.5.2, RbBP-30, RAP2A
Purification
Purified by antigen affinity column.
Accession
P10114
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Phosphorylation of synaptic GTPase-activating protein (synGAP) by polo-like kinase (Plk2) alters the ratio of its GAP activity toward HRas, Rap1 and Rap2 GTPases., PMID:30049443
Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum., PMID:29352039
Chemokine unresponsiveness of chronic lymphocytic leukemia cells results from impaired endosomal recycling of Rap1 and is associated with a distinctive type of immunological anergy., PMID:23804711
Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo., PMID:16507103
Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins., PMID:16213650
The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes., PMID:14701796
Activation of the Rap GTPases in B lymphocytes modulates B cell antigen receptor-induced activation of Akt but has no effect on MAPK activation., PMID:12904304
High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway., PMID:12196513
Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex., PMID:7962206
Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils., PMID:8391995
Partial purification of a GTPase-activating protein for rap2b from bovine brain membranes., PMID:1472043
Regulation of the GTPase activity of the ras-related rap2 protein., PMID:1449497
For research use only. Not for human or drug use.
