Catalog No.
PHC05702
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GBA (Ala40-Gln536).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Lysosomal acid glucosylceramidase, Lysosomal acid GCase, 3.2.1.45, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, Beta-glucosylceramidase 1, Cholesterol glucosyltransferase, SGTase, 2.4.1.-, Cholesteryl-beta-glucosidase, 3.2.1.-, D-glucosyl-N-acylsphingosine glucohydrolase, Glucosylceramidase beta 1, Imiglucerase, Lysosomal cholesterol glycosyltransferase, Lysosomal galactosylceramidase, 3.2.1.46, Lysosomal glycosylceramidase, GBA1, GBA, GC, GLUC
Purification
Purified by antigen affinity column.
Accession
P04062
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Rituximab as First-Line Compared to Escalation Immunotherapy Is Associated With Lower Disability Accumulation in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Multicenter Cohort Study From Germany and the United Kingdom., PMID:40492480
CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany., PMID:40470489
Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)., PMID:40292288
Effects of Anti-CD20 Antibody Therapy on Immune Cell Dynamics in Relapsing-Remitting Multiple Sclerosis., PMID:40214505
[Blood vessels as a target organ: from Ormond's disease to immunoglobulin G4-related diseases]., PMID:40167754
Challenges in Gaucher disease: Perspectives from an expert panel., PMID:40112481
Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN)., PMID:39996410
Identification of Cell Receptors Responsible for Recognition and Binding of Lipid Nanoparticles., PMID:39993835
Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model., PMID:39984138
Early comorbidities and diagnostic challenges in people with multiple sclerosis with possible impact on disease management., PMID:39944057
Immunotherapy-Resistant Neuropathic Pain and Fatigue Predict Quality-of-Life in Contactin-Associated Protein-Like 2 Antibody Disease., PMID:39825737
C5 complement inhibition versus FcRn modulation in generalised myasthenia gravis., PMID:39798960
Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD., PMID:39730197
Abatacept Induces Long-Term Reconstitution of the B-Cell Niche in a Patient With CTLA-4 Haploinsufficiency: A Case Report., PMID:39689284
African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1., PMID:39668204
Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions., PMID:39663541
Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer's disease., PMID:39659977
A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses., PMID:39567664
Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants., PMID:39509699
CSF and blood signatures support classification of limbic encephalitis subtypes., PMID:39401553
High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease., PMID:39388267
Eculizumab Use in Neuromyelitis Optica Spectrum Disorders: Routine Clinical Care Data From a European Cohort., PMID:39353149
An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes., PMID:39273438
[Can SARS-CoV-2 Infection Status in Preschool Children be Predicted by Pandemic-related Attitudes and Concerns of their Parents? Data from the Würzburg Daycare Centre Studies (Wü-KiTa-CoV, 2020-2022)]., PMID:39137922
HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis., PMID:39050850
Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation., PMID:39021292
Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy., PMID:38773124
Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease., PMID:38712038
SARS-CoV-2 Seroprevalence in a Berlin Kindergarten Environment: A Cross-Sectional Study, September 2021., PMID:38671622
Efgartigimod and Ravulizumab for Treating Acetylcholine Receptor Auto-antibody-Positive (AChR-Ab+) Generalized Myasthenia Gravis: Indirect Treatment Comparison., PMID:38642198
Ravulizumab in myasthenic crisis: the first case report., PMID:38388927
[Should patients with ANCA-associated vasculitis undergoing maintenance therapy with rituximab receive cotrimoxazole prophylaxis?]., PMID:38272971
Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke., PMID:38033615
Multi-omics for COVID-19: driving development of therapeutics and vaccines., PMID:37936830
Negative hyperselection of elderly patients with RAS and BRAF wild-type metastatic colorectal cancer receiving initial panitumumab plus FOLFOX or 5-FU/LV., PMID:37924647
Effect of Echinacea purpurea (L.) Moench and its extracts on the immunization outcome of avian influenza vaccine in broilers., PMID:37839770
An Efficient and Scalable Method for the Production of Immunogenic SARS-CoV-2 Virus-like Particles (VLP) from a Mammalian Suspension Cell Line., PMID:37766145
Neither alpha-synuclein-preformed fibrils derived from patients with GBA1 mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bulb., PMID:37662402
IGLV3-21R110 mutation has prognostic value in patients with treatment-naive chronic lymphocytic leukemia., PMID:37505099
Endo-radiofrequency subcision in the treatment of acne scars: a pilot investigative study., PMID:37400740
Osteonecrosis in Gaucher disease in the era of multiple therapies: Biomarker set for risk stratification from a tertiary referral center., PMID:37249220
Effect of Previous Disease-Modifying Therapy on Treatment Effectiveness for Patients Treated With Ocrelizumab., PMID:37041077
Autoimmune Encephalitis Misdiagnosis in Adults., PMID:36441519
SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications., PMID:36189209
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial., PMID:35946107
Molecular map of chronic lymphocytic leukemia and its impact on outcome., PMID:35927489
Highly Sensitive Love Mode Acoustic Wave Platform with SiO2 Wave-Guiding Layer and Gold Nanoparticles for Detection of Carcinoembryonic Antigens., PMID:35884339
Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study., PMID:35875815
Serum anti-NMDA-receptor antibodies and cognitive function after ischemic stroke (PROSCIS-B)., PMID:35718820
Label-free multiplex electrochemical immunosensor for early diagnosis of lysosomal storage disorders., PMID:35662258