Catalog No.
PHB79601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TGM6 (Ser494-Lys706).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein-glutamine gamma-glutamyltransferase 6, 2.3.2.13, Transglutaminase Y, TGY, TGase Y, Transglutaminase-3-like, TGase-3-like, Transglutaminase-6, TG6, TGase-6, TGM6, TGM3L
Purification
Purified by antigen affinity column.
Accession
O95932
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Serological analysis of gluten-related antibodies in idiopathic neuropathies and cerebellar ataxia., PMID:40481865
CSF Markers of TG6 Autoimmunity in Gluten Ataxia., PMID:40172737
[Association between anti-tissue transglutaminase antibody titers and duodenal histopathology among adults with celiac disease]., PMID:36746530
Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology., PMID:34298918
TG6 Auto-Antibodies in Dermatitis Herpetiformis., PMID:32967363
Dietary Gluten and Neurodegeneration: A Case for Preclinical Studies., PMID:32751379
Epilepsy, cerebral calcifications, and gluten-related disorders: Are anti-transglutaminase 6 antibodies the missing link?, PMID:31698178
Neurologic Deficits in Patients With Newly Diagnosed Celiac Disease Are Frequent and Linked With Autoimmunity to Transglutaminase 6., PMID:30885888
Autoantibodies in the Extraintestinal Manifestations of Celiac Disease., PMID:30127251
Transglutaminase 6 antibodies in gluten neuropathy., PMID:28886934
[Gluten Ataxia: Anti-Transglutaminase-6 Antibody as a New Biomarker]., PMID:28819077
Anti-transglutaminase 6 Antibody Development in Children With Celiac Disease Correlates With Duration of Gluten Exposure., PMID:28542044
Transglutaminase-6 is an autoantigen in progressive multiple sclerosis and is upregulated in reactive astrocytes., PMID:28273770
No association between gluten sensitivity and amyotrophic lateral sclerosis., PMID:28168522
[A case considered gluten ataxia with anti-TG6 IgA antibodies]., PMID:27212675
Transglutaminase 6 Antibodies in the Serum of Patients With Amyotrophic Lateral Sclerosis., PMID:25867286
Gluten ataxia of sporadic and hereditary cerebellar ataxia in patients from mainland China., PMID:23860139
Distribution of transglutaminase 6 in the central nervous system of adult mice., PMID:23836538
Transglutaminase 6 antibodies in the diagnosis of gluten ataxia., PMID:23576621
Coeliac disease, epilepsy, and cerebral calcifications: association with TG6 autoantibodies., PMID:22845673
Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients., PMID:22516148
IgA-class autoantibodies against neuronal transglutaminase, TG6 in celiac disease: no evidence for gluten dependency., PMID:21453693
Gluten sensitivity and the CNS: diagnosis and treatment., PMID:20610339
New serology assays can detect gluten sensitivity among enteropathy patients seronegative for anti-tissue transglutaminase., PMID:20022983
Autoantibodies in gluten ataxia recognize a novel neuronal transglutaminase., PMID:18825674