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Anti-Human ECD Polyclonal Antibody

Catalog #:   PHB78901 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O95905
Overview

Catalog No.

PHB78901

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ECD (Met10-Asn406).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein ecdysoneless homolog, Human suppressor of GCR two, hSGT1, ECD

Purification

Purified by antigen affinity column.

Accession

O95905

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ECD antibody (PHB78901) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 48 kDa
    Observed MW: 48 kDa
References

Validated Immunochemical Assay for Comprehensive Determination of the Human Epidermal Growth Factor Receptor 2 Released from and Bound to Cells., PMID:40418656

Top-Down and Middle-Down Mass Spectrometry of Antibodies., PMID:40368137

Mass-Forming Variants in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Diagnostic Complexities in Granulomatous Disease. A Case Report., PMID:40183740

A Prognostic Index for Deceased Donor Kidneys and Criteria for Identifying Suitable Candidates for Kidney Transplantation from Expanded Criteria Donors with Prolonged Waiting Times., PMID:40160491

Early 2022 breakthrough infection sera from India target the conserved cryptic class 5 epitope to counteract immune escape by SARS-CoV-2 variants., PMID:40135898

Characterization of alternative sPD-1 isoforms reveals that ECD sPD-1 signature predicts an efficient antitumor response., PMID:40069413

Identification of potent biparatopic antibodies targeting FGFR2 fusion-driven cholangiocarcinoma., PMID:40014401

Nauclofficines A and B, two novel monoterpenoid indole alkaloids from the Li folk herb Nauclea officinalis with anti-allergic inflammatory effects on RBL-2H3 cells., PMID:39987995

Electrochemical flow injection analysis platforms for biomedical applications - Progress and prospects., PMID:39894143

Impact of Organ Donor Pretreatment With Anti-Thymocyte Globulin in a Murine Model of Allogenic Kidney Transplantation., PMID:39839912

Mechanisms in Thyroid Eye Disease: The TSH Receptor Interacts Directly With the IGF-1 Receptor., PMID:39821041

Clinical Evaluation of the HER2 Extracellular Domain in Breast Cancer Patients by Herceptin-Encapsulated Gold Nanocluster Probe-Based Electrochemiluminescence Immunoassay., PMID:39739962

Efficacy of Combined Encorafenib and Binimetinib Treatment for Erdheim-Chester Disease Harboring Concurrent BRAFV600E and KRASG12R Mutations: A Case Report., PMID:39724464

Development and evaluation of a single domain antibody targeting folate receptor alpha for radioligand therapy., PMID:39696571

Bullous pemphigoid and mucous membrane pemphigoid humoral responses differ in reactivity towards BP180 midportion and BP230., PMID:39676877

Breadth of immune response, immunogenicity, reactogenicity, and safety for a pentavalent meningococcal ABCWY vaccine in healthy adolescents and young adults: results from a phase 3, randomised, controlled observer-blinded trial., PMID:39647494

Effects on corneal endothelium of intravitreal injection of anti-VEGF drugs., PMID:39560148

A statistically established reference value determined for the Vaxarray Coronavirus (CoV) seroassay to characterize vaccination and natural infection., PMID:39548371

Antitumor activity of PAbs generated by immunization with a novel HER3-targeting protein-based vaccine candidate in preclinical models., PMID:39479017

Novel Anti-Trop2 Nanobodies Disrupt Receptor Dimerization and Inhibit Tumor Cell Growth., PMID:39458590

Selective targeting of oncogenic hotspot mutations of the HER2 extracellular domain., PMID:39438724

Unveiling the impact of Leptospira TolC efflux protein on host tissue adherence, complement evasion, and diagnostic potential., PMID:39392312

IGSF9 promotes tumor invasion and metastasis through GSK-3β/β-catenin mediated EMT in lung cancer., PMID:39383800

Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma., PMID:39345400

Pushing the Survival Bar Higher: Two Decades of Innovation in Lung Transplantation., PMID:39337005

Development of novel multi-protein chimeric immunogens that protect against infection with the Lyme disease agent, Borreliella burgdorferi., PMID:39287439

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors., PMID:39281883

p75ECD-Fc reverses neonatal hypoxic-ischemic encephalopathy-induced neurological deficits and inhibits apoptosis associated with Nestin., PMID:39278187

A Non-Canonical p75HER2 Signaling Pathway Underlying Trastuzumab Action and Resistance in Breast Cancer., PMID:39273024

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors., PMID:39231834

Evaluation of Methodologies in Anti-nephrin Autoantibody Detection., PMID:39211159

Elucidating the Immune Response to SARS-CoV-2: Natural Infection versus Covaxin/Covishield Vaccination in a South Indian Population., PMID:39205152

Comprehensive Glycomic and Glycoproteomic Analyses of Human Programmed Cell Death Protein 1 Extracellular Domain., PMID:39101792

Switching anti-EGFR antibody re-sensitizes head and neck cancer patient following acquired resistance to cetuximab., PMID:39085630

HER2-CD3-Fc Bispecific Antibody-Encoding mRNA Delivered by Lipid Nanoparticles Suppresses HER2-Positive Tumor Growth., PMID:39066446

Identification of monoclonal antibodies from naive antibody phage-display libraries for protein detection in formalin-fixed paraffin-embedded tissues., PMID:39059744

Sustainability-Driven Accelerated Shear-Mediated Immunoassay for Amyotrophic Lateral Sclerosis Detection., PMID:38987226

Antibody fragments targeting the extracellular domain of follicular stimulating hormone receptor for contraception in male dogs and cats., PMID:38875921

Clinical development of SpikoGen®, an Advax-CpG55.2 adjuvanted recombinant spike protein vaccine., PMID:38839044

Hemolin increases the immune response of a caterpillar to NPV infection., PMID:38763360

Humoral responses to multiple SARS-CoV-2 variants after two doses of vaccine in kidney transplant patients., PMID:38717195

Long-term dynamic changes and influencing factors of corneal morphology after multiple intravitreal injections of anti-VEGF drugs., PMID:38669379

Establishment of an intragastric surgical model using C57BL/6 mice to study the vaccine efficacy of OMV-based immunogens against Helicobacter pylori., PMID:38602383

Cancer-associated point mutations within the extracellular domain of PTPRD affect protein stability and HSPG interaction., PMID:38593345

Exploratory analysis of serum HER2 extracellular domain for HER2 positive gastric cancer treated with SOX plus trastuzumab., PMID:38589679

Status of B-Lymphocyte Subsets and Their Homing Markers in Patients With Post-Kala-Azar Dermal Leishmaniasis., PMID:38527908

Expanding Differential Ion Mobility Separations into the MegaDalton Range., PMID:38526848

An innovative antibody fusion protein targeting PD-L1, VEGF and TGF-β with enhanced antitumor efficacies., PMID:38377856

The unique monoclonal antibodies and immunochemical assay for comprehensive determination of the cell-bound and soluble HER2 in different biological samples., PMID:38368450

Do intravitreal anti-VEGF injections have an effect on corneal endothelial remodeling in children with premature retinopathy?, PMID:38303540

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human ECD Polyclonal Antibody [PHB78901]
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