Catalog No.
PHB64301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TNFRSF6B (Val30-His300).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6, UNQ186/PRO212
Purification
Purified by antigen affinity column.
Accession
O95407
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Identification of a costimulatory molecule-based signature for predicting prognosis risk and immunotherapy response in patients with lung adenocarcinoma., PMID:33457102
Association of Tumor Necrosis Like factor 1 A (TL1A) and its Decoy Receptor (DcR3) with The Disease Activity and Autoantibody Production in Rheumatoid Arthritis Patients., PMID:31332995
Decoy receptor 3 down-regulates centrosomal protein 70 kDa specifically in rheumatoid synovial fibroblasts., PMID:28696795
DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426
Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro., PMID:28223726
Serum decoy receptor 3 is a biomarker for disease severity in nonatopic asthma patients., PMID:26911723
Tumor Necrosis Factor-like Cytokine TL1A and Its Receptors DR3 and DcR3: Important New Factors in Mucosal Homeostasis and Inflammation., PMID:26099067
Effect of TNFRSF6B neutralization antibody on cell growth suppression and apoptosis induction in glioma cells., PMID:25997959
Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS., PMID:25823874
Serum and synovial fluid levels of tumor necrosis factor-like ligand 1A and decoy receptor 3 in rheumatoid arthritis., PMID:25647275
Systemic and local expression levels of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis., PMID:24016146
DcR3 induces cell proliferation through MAPK signaling in chondrocytes of osteoarthritis., PMID:21420502
Expression of DcR3 and its effects in kaposi's sarcoma-associated herpesvirus-infected human endothelial cells., PMID:21293109
Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition., PMID:20962851
TNFRSF6B neutralization antibody inhibits proliferation and induces apoptosis in hepatocellular carcinoma cell., PMID:20591579
DcR3 protects THP-1 macrophages from apoptosis by increasing integrin alpha4., PMID:19748482
Ascites from epithelial ovarian cancer contain high levels of functional decoy receptor 3 (DcR3) and is associated with platinum resistance., PMID:18723214
DcR3 as a diagnostic parameter and risk factor for systemic lupus erythematosus., PMID:18562337
[Preparation and identification of monoclonal antibodies against human DcR3]., PMID:18237531
Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3)., PMID:18006694
Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer., PMID:17490732
Significant inhibition of human CD8(+) cytotoxic T lymphocyte-mediated xenocytotoxicity by overexpression of the human decoy Fas antigen., PMID:16534484
Prognostic impact of FAS/CD95/APO-1 in urothelial cancers: decreased expression of Fas is associated with disease progression., PMID:16091761
Soluble decoy receptor 3: increased levels in atopic patients., PMID:15282937
Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action., PMID:14871847
Quantification and detection of DcR3, a decoy receptor in TNFR family., PMID:14871535
Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3., PMID:14613271
Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma., PMID:12794752
Mouse T cells receive costimulatory signals from LIGHT, a TNF family member., PMID:12384428
In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor., PMID:11408521
Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells., PMID:11190279
For research use only. Not for human or drug use.
