Catalog No.
PHB47601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TOX (Val265-Val341).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX, TOX, KIAA0808
Purification
Purified by antigen affinity column.
Accession
O94900
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Utilizing non-clonal CHO cell derived materials for preclinical studies of complex molecules., PMID:40335959
Q-TWiST Analysis of Sacituzumab Govitecan vs. Chemotherapy in Previously Treated Patients with HR+/HER2- Metastatic Breast Cancer., PMID:40136373
The preclinical discovery and development of secukinumab for the treatment of moderate-to-severe hidradenitis suppurativa., PMID:40106842
TIGIT expression in extrahepatic cholangiocarcinoma and its impact on CD8 + T cell exhaustion: implications for immunotherapy., PMID:39939322
PD-1 cis-targeted IL-2v in combination with radiotherapy inhibits lung cancer growth and remodels the immune microenvironment., PMID:39848686
Quality-adjusted time without symptoms or toxicity analysis of trastuzumab deruxtecan versus trastuzumab emtansine in HER2- positive metastatic breast cancer patients based on secondary use of the DESTINY-Breast03 trial., PMID:39798264
Effect of Gold Nanoparticles on Luminescence Enhancement in Antibodies for TORCH Detection., PMID:39683881
Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA.5 sublineages., PMID:39536392
Intratumoral STING agonist reverses immune evasion in PD-(L)1-refractory Merkel cell carcinoma: mechanistic insights from detailed biomarker analyses., PMID:39401968
Protection efficacy and immunogenicity of Clostridium chauvoei proteins as a subunit blackleg vaccine or an adjuvant for Clostridium perfringens epsilon toxoid., PMID:39395742
Seroprevalence and age-related susceptibility of TORCH infections in childbearing age women: A 5-year cross-sectional retrospective study and a literature review., PMID:39255545
[Snakebite in Switzerland - a potentially life-threatening event?]., PMID:39166786
Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells., PMID:39143416
Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity., PMID:39121849
Advancing PFAS risk assessment: Integrative approaches using agent-based modelling and physiologically-based kinetic for environmental and health safety., PMID:39050784
The TOX-RAGE axis mediates inflammatory activation and lung injury in severe pulmonary infectious diseases., PMID:38900789
Study of late toxicity biomarkers of locally advanced head and neck cancer patients treated with radiotherapy plus cisplatin or cetuximab points to the relevance of skin macrophages (TOX-TTCC-2015-01)., PMID:38782865
Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses., PMID:38653864
Serological Screening of TORCH Pathogen Infections in Infertile Women of Childbearing Age in Northwest China., PMID:38630173
Diagnostic Validation of Anti-TOX Antibody for Early-Stage Mycosis Fungoides Through Digital Analysis of Tissue Samples., PMID:38457684
Rapid loss of maternal immunity and increase in environmentally mediated antibody generation in urban gulls., PMID:38388645
Carbon nanospheres dual spectral-overlapped fluorescence quenching lateral flow immunoassay for rapid diagnosis of toxoplasmosis in humans., PMID:38310830
Accelerating the speed of innovative anti-tumor drugs to first-in-human trials incorporating key de-risk strategies., PMID:38095560
TOX, TWIST1, STAT4, and SATB1 protein expressions in early-stage mycosis fungoides., PMID:37932931
Efficacy, Pharmacokinetics, and Toxicity Profiles of a Broad Anti-SARS-CoV-2 Neutralizing Antibody., PMID:37632075
Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy., PMID:37625402
Prevalence of preconception TORCH infections and its influential factors: evidence from over 2 million women with fertility desire in southern China., PMID:37563634
Terminally exhausted CD8+ T cells contribute to age-dependent severity of respiratory virus infection., PMID:37528458
Serological status for TORCH in women of childbearing age: a decade-long surveillance (2012-2022) in Italy., PMID:37458733
[The expression and correlation analysis of TOX and inhibitory receptors on peripheral blood CD8+T cells in patients with aplastic anemia]., PMID:37455127
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation., PMID:37392737
A retrospective study of air quality associated with teratogenic pathogen screening in women of reproductive age in southern China., PMID:37347331
Quality-adjusted survival time without symptoms or toxicity of acalabrutinib with or without obinutuzumab in patients with treatment-naive chronic lymphocytic leukemia., PMID:37221877
CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4+ T cells., PMID:37161048
Association of common infections with cognitive performance in the Baltimore Epidemiologic Catchment Area study follow-up., PMID:37027458
Seroprevalence of ToRCH Pathogens among Children Admitted to a Tertiary Care Hospital in Eastern India for Cataract Surgery and Cochlear Transplantation., PMID:36809946
Silver Nanoparticles Phytofabricated through Azadirachta indica: Anticancer, Apoptotic, and Wound-Healing Properties., PMID:36671322
Botulinum toxin antibody titres: measurement, interpretation, and practical recommendations., PMID:36434127
Routine first-line detection of breast cancer therapy-related cardiotoxicity by serial, fast and ultra-low-dose equilibrium radionuclide angiography., PMID:36289164
Endemic erythromycin resistant Corynebacterium diphtheriae in Vietnam in the 1990s., PMID:36259695
The immunology of botulinum toxin therapy: A brief summary., PMID:36191878
Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function., PMID:36150362
Determination of Diphtheria Toxin in Bacterial Cultures by Enzyme Immunoassay., PMID:36140605
Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma., PMID:36122387
Detection of diphtheria toxin production by toxigenic corynebacteria using an optimized Elek test., PMID:36053480
Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus., PMID:36042047
GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2., PMID:35890050
TOX Expression in Mycosis Fungoides and Sezary Syndrome., PMID:35885488
Exhausted PD-1+ TOX+ CD8+ T Cells Arise Only in Long-Term Experimental Trypanosoma cruzi Infection., PMID:35720419
Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients., PMID:35154905
For research use only. Not for human or drug use.
