Catalog No.
PHB36501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAD17 (Lys96-Pro353).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cell cycle checkpoint protein RAD17, hRad17, RF-C/activator 1 homolog, RAD17, R24L
Purification
Purified by antigen affinity column.
Accession
O75943
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Telomere Dysfunction Induced Foci (TIF) Analysis., PMID:27500188
Interaction of Ddc1 and RPA with single-stranded/double-stranded DNA junctions in yeast whole cell extracts: Proteolytic degradation of the large subunit of replication protein A in ddc1Δ strains., PMID:25089887
Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance., PMID:23383325
Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis., PMID:23047948
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage., PMID:19020305
DNA damage foci at dysfunctional telomeres., PMID:12956959
Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabditis elegans linker histones suggests a mechanistic connection between germ line and telomeric silencing., PMID:12724425
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin., PMID:11799063
Multiple alternative splicing forms of human RAD17 and their differential response to ionizing radiation., PMID:11602352
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage., PMID:9755168
For research use only. Not for human or drug use.
