Catalog No.
PHB30401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAD51D (Thr79-Thr328).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DNA repair protein RAD51 homolog 4, R51H3, RAD51 homolog D, RAD51-like protein 3, TRAD, RAD51D, RAD51L3
Purification
Purified by antigen affinity column.
Accession
O75771
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial., PMID:36716415
Mutations in DNA Repair Genes and Clinical Outcomes of Patients With Metastatic Colorectal Cancer Receiving Oxaliplatin or Irinotecan-containing Regimens., PMID:33298767
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy., PMID:23108668
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions., PMID:19863810
The RAD51 gene family in bread wheat is highly conserved across eukaryotes, with RAD51A upregulated during early meiosis., PMID:32688873
Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica., PMID:18402694
Nuclear localization of Rad51B is independent of Rad51C and BRCA2., PMID:15701685
Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination., PMID:15657438
Telomere maintenance requires the RAD51D recombination/repair protein., PMID:15109494
RAD51 localization and activation following DNA damage., PMID:15065660
RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51., PMID:11744692