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Anti-Human RAD51D Polyclonal Antibody

Catalog #:   PHB30401 Specific References (11) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O75771
Overview

Catalog No.

PHB30401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RAD51D (Thr79-Thr328).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

DNA repair protein RAD51 homolog 4, R51H3, RAD51 homolog D, RAD51-like protein 3, TRAD, RAD51D, RAD51L3

Purification

Purified by antigen affinity column.

Accession

O75771

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with RAD51D antibody (PHB30401) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 29 kDa
    Observed MW: 29 kDa
References

Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial., PMID:36716415

Mutations in DNA Repair Genes and Clinical Outcomes of Patients With Metastatic Colorectal Cancer Receiving Oxaliplatin or Irinotecan-containing Regimens., PMID:33298767

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy., PMID:23108668

RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions., PMID:19863810

The RAD51 gene family in bread wheat is highly conserved across eukaryotes, with RAD51A upregulated during early meiosis., PMID:32688873

Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica., PMID:18402694

Nuclear localization of Rad51B is independent of Rad51C and BRCA2., PMID:15701685

Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination., PMID:15657438

Telomere maintenance requires the RAD51D recombination/repair protein., PMID:15109494

RAD51 localization and activation following DNA damage., PMID:15065660

RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51., PMID:11744692

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human RAD51D Polyclonal Antibody [PHB30401]
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