Catalog No.
PHJ82101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD201/PROCR (Ser18-Ser210).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Endothelial protein C receptor,PROCR,EPCR,APC receptor,Endothelial cell protein C receptor,CD201,Activated protein C receptor
Purification
Purified by antigen affinity column.
Accession
Q9UNN8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Endothelial protein C receptor promotes retinal neovascularization through heme catabolism., PMID:39948347
Broadly inhibitory antibodies to severe malaria virulence proteins., PMID:39567685
A systems serology approach to identifying key antibody correlates of protection from cerebral malaria in Malawian children., PMID:39267089
Mosaic and cocktail capsid-virus-like particle vaccines for induction of antibodies against the EPCR-binding CIDRα1 domain of PfEMP1., PMID:39046960
An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease-activated receptor-derived peptides mimics in vitro and in vivo activities of activated protein C., PMID:38670314
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation., PMID:34257318
Activated protein C and PAR1-derived and PAR3-derived peptides are anti-inflammatory by suppressing macrophage NLRP3 inflammasomes., PMID:33049092
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis., PMID:32152303
Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria., PMID:30365003
The H1 haplotype of the endothelial protein C receptor protects against arterial thrombosis in patients with antiphospholipid syndrome., PMID:30048851
Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity., PMID:29879294
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea., PMID:29784862
Endothelial Protein C-Targeting Liposomes Show Enhanced Uptake and Improved Therapeutic Efficacy in Human Retinal Endothelial Cells., PMID:29677376
Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent Progress., PMID:29538262
Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner., PMID:29484413
Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo., PMID:28408624
Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal Muscle., PMID:27509136
Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells., PMID:26663133
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding., PMID:26646943
Plasmodium falciparum adhesion domains linked to severe malaria differ in blockade of endothelial protein C receptor., PMID:26118955
IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria., PMID:26015475
Endothelial cell protein C receptor promotes MGC803 gastric cancer cells proliferation and migration by activating ERK1/2., PMID:25895599
CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1., PMID:25892186
Thalidomide and multiple myeloma serum synergistically induce a hemostatic imbalance in endothelial cells in vitro., PMID:25840743
[Peptide-agonist of protease-activated receptor (PAR 1), similar to activated protein C, promotes proliferation in keratinocytes and wound healing of epithelial layer]., PMID:25552512
Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria., PMID:25482433
Role of the protein C receptor in cancer progression., PMID:24862151
Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2., PMID:24495480
Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor., PMID:24244621
Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection., PMID:23717683
Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition., PMID:23661674
Endothelial protein C receptor function in murine and human breast cancer development., PMID:23593394
Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?, PMID:23408932
The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis., PMID:23348224
Multifluorescence confocal microscopy: application for a quantitative analysis of hemostatic proteins in human venous valves., PMID:23026998
Comprehensive phenotypic characterization of human adipose-derived stromal/stem cells and their subsets by a high throughput technology., PMID:22920587
Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor., PMID:22885985
Endothelial protein C receptor expressed by ovarian cancer cells as a possible biomarker of cancer onset., PMID:22614534
Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis., PMID:22298906
Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C., PMID:21885613
Protective cross talk between activated protein C and TNF signaling in vascular endothelial cells: implication of EPCR, noncanonical NF-κB, and ERK1/2 MAP kinases., PMID:21228323
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors., PMID:21149441
Francisella tularensis suppresses the proinflammatory response of endothelial cells via the endothelial protein C receptor., PMID:20543103
Role of coagulation factors in cerebral venous sinus and cerebral microvascular thrombosis., PMID:20124931
The endothelial cells downregulate the generation of factor VIIa through EPCR binding., PMID:20085578
Liver myofibroblasts activate protein C and respond to activated protein C., PMID:20066740
Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor., PMID:19895674
Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function., PMID:19858095
Activated protein C stimulates osteoblast proliferation via endothelial protein C receptor., PMID:19804899
For research use only. Not for human or drug use.
