Catalog No.
PHA70401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human XRCC2 (His40-Cys280).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
DNA repair protein XRCC2, X-ray repair cross-complementing protein 2, XRCC2
Purification
Purified by antigen affinity column.
Accession
O43543
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Relationship between autoimmunity and COPD: an investigation based on proteomic profiling and antinuclear antibody screening., PMID:40329569
Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt's B cell lymphoma., PMID:32782434
Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model., PMID:27467592
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy., PMID:23108668
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions., PMID:19863810
Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs., PMID:18840549
Artesunate derived from traditional Chinese medicine induces DNA damage and repair., PMID:18519695
Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica., PMID:18402694
Homologous recombination is necessary for normal lymphocyte development., PMID:18212067
Nuclear localization of Rad51B is independent of Rad51C and BRCA2., PMID:15701685
Similar effects of Brca2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination., PMID:15657438
hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51., PMID:15123651
Telomere maintenance requires the RAD51D recombination/repair protein., PMID:15109494
RAD51 localization and activation following DNA damage., PMID:15065660
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase., PMID:12214226
RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51., PMID:11744692
In vitro evidence for homologous recombinational repair in resistance to melphalan., PMID:11584063
Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation., PMID:11528482
For research use only. Not for human or drug use.
