Catalog No.
PXX21001
Species reactivity
Clostridium perfringens
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Clostridium perfringens cpb/Beta-toxin (Asn28-Ile336).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:500-1:4000
Target
beta-channel forming cytolysin CPB, cpb
Concentration
0.66 mg/ml
Purification
Purified by antigen affinity column.
Accession
WP_004456321.1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
An in vitro assay for toxicity testing of Clostridium perfringens type C β-toxin., PMID:38646535
A non-toxic recombinant protein rSUMO-CPBm4 as a potential vaccine candidate against Clostridium perfringens type C beta enterotoxemia., PMID:38308826
Novel toxin-based mRNA vaccine against Clostridium perfringens using in silico approaches., PMID:38185287
Immunization of sheep with a recombinant vaccine containing immunogenic nontoxic domains of Clostridium perfringens alpha and beta toxins., PMID:37516212
Platelet Endothelial Cell Adhesion Molecule 1 (CD31) Is Essential for Clostridium perfringens Beta-Toxin Mediated Cytotoxicity in Human Endothelial and Monocytic Cells., PMID:34941730
Measurement over 1 Year of Neutralizing Antibodies in Cattle Immunized with Trivalent Vaccines Recombinant Alpha, Beta and Epsilon of Clostridium perfringens., PMID:34564599
Humoral Immune Response Evaluation in Horses Vaccinated with Recombinant Clostridium perfringens Toxoids Alpha and Beta for 12 Months., PMID:34437437
Evaluation of the expression and immunogenicity of four versions of recombinant Clostridium perfringens beta toxin designed by bioinformatics tools., PMID:33508438
Immunization of mice against alpha, beta, and epsilon toxins of Clostridium perfringens using recombinant rCpa-b-x expressed by Bacillus subtilis., PMID:32447084
Vaccination against Clostridium perfringens type C enteritis in pigs: a field study using an adapted vaccination scheme., PMID:31428441
Application of an Endothelial Cell Culture Assay for the Detection of Neutralizing Anti-Clostridium Perfringens Beta-Toxin Antibodies in a Porcine Vaccination Trial., PMID:30991691
Clostridium perfringens beta toxin DNA prime-protein boost elicits enhanced protective immune response in mice., PMID:28523396
The CpAL system regulates changes of the trans-epithelial resistance of human enterocytes during Clostridium perfringens type C infection., PMID:27063897
Generation and characterization of recombinant bivalent fusion protein r-Cpib for immunotherapy against Clostridium perfringens beta and iota toxemia., PMID:26774054
Synergistic effects of Clostridium perfringens enterotoxin and beta toxin in rabbit small intestinal loops., PMID:24778117
[Occurrence and control of the Clostridium perfringens type A associated diarrhea of the suckling pigs with special consideration of the immunoprophylaxis]., PMID:23242147
Potential protective immunogenicity of recombinant Clostridium perfringens α-β2-β1 fusion toxin in mice, sows and cows., PMID:21641956
Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias., PMID:19805537
Involvement of tumour necrosis factor-alpha in Clostridium perfringens beta-toxin-induced plasma extravasation in mice., PMID:18264118
Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model., PMID:18078439
Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model., PMID:17210666
Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model., PMID:16926413
Cloning of alpha-beta fusion gene from Clostridium perfringens and its expression., PMID:16534876
Development and prevalidation of two different ELISA systems for the potency testing of Clostridium perfringens beta and epsilon-toxoid containing veterinary vaccines., PMID:10397315
Development and evaluation of various enzyme-linked immunosorbent assays for the detection of Clostridium perfringens beta anti-toxins., PMID:10397314
Measurement of Clostridium perfringens beta-toxin production by surface plasmon resonance immunoassay., PMID:9682350
Development of double sandwich ELISA for Clostridium perfringens beta and epsilon toxins., PMID:1615638
Enzyme-linked immunosorbent assay for rapid detection of toxins from Clostridium perfringens., PMID:1769554
Protection of the nursing pig against experimentally induced enteric colibacillosis by vaccination of dam with fimbrial antigens of E coli (K88, K99 and 987P)., PMID:3907113