Anti-EBF1 Polyclonal Antibody

Catalog No.

PHJ75401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EBF1 (Asp179-Ser451).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

EBF,EBF1,OE-1,COE1,Early B-cell factor,Transcription factor COE1,O/E-1

Purification

Purified by antigen affinity column.

Accession

Q9UH73

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Differentiation-dependent EBF1 Activity Determines CD22 Transcription and Leukemia Sensitivity to Inotuzumab Ozogamicin., PMID:40435412

Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932

Three-dimensional chromatin reorganization regulates B cell development during ageing., PMID:38866970

A human-specific insertion promotes cell proliferation and migration by enhancing TBC1D8B expression., PMID:38110796

EBF1, MYO6 and CALR expression levels predict therapeutic response in diffuse large B-cell lymphomas., PMID:38035116

Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling., PMID:36167471

Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus., PMID:36165173

Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions., PMID:35650277

IL-7R signaling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells., PMID:34260907

Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan., PMID:33707599

Abnormal thymic B cell activation and impaired T cell differentiation in pristane-induced lupus mice., PMID:33428991

Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain., PMID:32198144

Immunogenetics of marsupial B-cells., PMID:31726269

Potential Markers of Autoimmune Diseases, Alleles rs115662534(T) and rs548231435(C), Disrupt the Binding of Transcription Factors STAT1 and EBF1 to the Regulatory Elements of Human CD40 Gene., PMID:30878028

Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas., PMID:29946193

Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming., PMID:29440261

Application of gene specific mRNA level determinations in individual cells using flow cytometry-based PrimeFlow™ in immunotoxicology., PMID:29107001

Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival., PMID:28369050

Applied Protein and Molecular Techniques for Characterization of B Cell Neoplasms in Horses., PMID:26311245

The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth., PMID:25985234

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency., PMID:25838350

Hind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging., PMID:25376832

The survival and differentiation of pro-B and pre-B cells in the bone marrow is dependent on IL-7Rα Tyr449., PMID:25143441

B cell signatures of BCWD-resistant and susceptible lines of rainbow trout: a shift towards more EBF-expressing progenitors and fewer mature B cells in resistant animals., PMID:25101978

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals., PMID:24297995

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner., PMID:24078629

A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma., PMID:23775715

Cellular origin and pathophysiology of chronic lymphocytic leukemia., PMID:23091163

MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes., PMID:23071088

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia., PMID:22851563

Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., PMID:22808135

Essential role of EBF1 in the generation and function of distinct mature B cell types., PMID:22473956

Expression of essential B cell development genes in horses with common variable immunodeficiency., PMID:22464097

Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., PMID:22431510

The complexity of Sjögren's syndrome: novel aspects on pathogenesis., PMID:21777618

The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow., PMID:21423172

Identification of direct downstream targets of Dlx5 during early inner ear development., PMID:21227998

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome., PMID:20861858

Chromosome dynamics and the regulation of V(D)J recombination., PMID:20727028

Comparative analyses of B cell populations in trout kidney and mouse bone marrow: establishing "B cell signatures"., PMID:20705088

Emerging roles of the EBF family of transcription factors in tumor suppression., PMID:19996307

Early B cell factor: Regulator of B lineage specification and commitment., PMID:18722139

Two levels of protection for the B cell genome during somatic hypermutation., PMID:18273020

Expression of SNC73, a transcript of the immunoglobulin alpha-1 gene, in human epithelial carcinomas., PMID:17511028

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits., PMID:17363301

HDAC2 controls IgM H- and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions., PMID:17352740

The HSS3/4 enhancer of Crlz1-IgJ locus is another target of EBF in the pre-B cell stage of B cell development., PMID:16962668

Evi3, a zinc-finger protein related to EBFAZ, regulates EBF activity in B-cell leukemia., PMID:15580294

Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression., PMID:15544702

Assembly and analysis of the mouse immunoglobulin kappa gene sequence., PMID:15378297

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