Catalog No.
PHJ69701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IL36G/IL-1F9 (Met1-Ala162).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Interleukin-1 homolog 1,IL1H1,IL-1H1,IL-1RP2,IL-1 epsilon,IL1E,IL-1F9,IL36G,IL-1-related protein 2,Interleukin-1 family member 9,IL1RP2,Interleukin-36 gamma,Interleukin-1 epsilon,IL1F9
Purification
Purified by antigen affinity column.
Accession
Q9NZH8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
An S100A8/A9 Neutralizing Antibody Potently Ameliorates Contact Hypersensitivity and Atopic Dermatitis Symptoms., PMID:39848567
Targeting the STAT3/IL-36G signaling pathway can be a promising approach to treat rosacea., PMID:38909883
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory., PMID:38892277
Understanding the impact of risankizumab on keratinocyte-derived IL-23A in a novel organotypic 3D skin model containing IL-23A responsive and IL-17A producing γδ-T-cells., PMID:38284163
Mature IL-36γ Induces Stratum Corneum Exfoliation in Generalized Pustular Psoriasis by Suppressing Corneodesmosin., PMID:37827276
Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes., PMID:36496195
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis., PMID:36470344
TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy., PMID:34797693
IL-36γ and IL-36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress-Induced Cell Death., PMID:34369094
Interleukin-1 Blockade in Polygenic Autoinflammatory Disorders: Where Are We now?, PMID:33708123
Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses., PMID:32352958
IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema., PMID:31793105
IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment., PMID:30377293
Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation., PMID:30223113
Detection of IL-36γ through noninvasive tape stripping reliably discriminates psoriasis from atopic eczema., PMID:29782895
An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target., PMID:29021166
Altered expression of IL36γ and IL36 receptor (IL1RL2) in the colon of patients with Hirschsprung's disease., PMID:27853811
IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo., PMID:26783184
IL-36γ sustains a proinflammatory self-amplifying loop with IL-17C in anti-TNF-induced psoriasiform skin lesions of patients with Crohn's disease., PMID:25299544
Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling., PMID:23383400
Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9., PMID:22144259
For research use only. Not for human or drug use.
