Catalog No.
YHB97404
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1250-Leu1464
Predicted molecular weight
26.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02452
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
METTL3 promotes the hypertrophic scar fibrosis via m6A RNA methylation of GRAMD1B mRNA., PMID:40515792
Klotho promotes bone formation in rheumatoid arthritis-associated osteoporosis by modulating the Fgf23/Fgfr1/NF-κB pathway and inhibiting ferroptosis., PMID:40513341
Effect of recombinant human parathyroid hormone and zoledronic acid on osteoblast gene expression using multifaceted approach: An in vitro study., PMID:40509760
The Impact of Selected COL1A1 and COL1A2 Gene Polymorphisms on Bone Mineral Density and the Risk of Metabolic Diseases in Postmenopausal Women., PMID:40507792
Bioinformatics analysis of hub genes and oxidative stress-related pathways in odontogenic keratocysts., PMID:40505773
TGF-β1/BSA coating modulates multi-phasic scaffolds for osteochondral tissue regeneration., PMID:40502370
Activation of the Wnt signaling pathway and its role in epithelial-mesenchymal transition and hepatic fibrosis in alveolar echinococcosis., PMID:40496021
Laser-stimulated human gingival fibroblasts: alterations in migration, secretome production, and induction of reactive oxygen species., PMID:40488797
P4HA1 mediates YAP hydroxylation and accelerates collagen synthesis in temozolomide-resistant glioblastoma., PMID:40484999
Mast cell tryptase-PAR2 axis promotes ovarian fibrosis through RNF152-mediated stabilization of Bcl-xL., PMID:40474218
Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis., PMID:40473047
A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study., PMID:40465952
Unique TMJ-specific transcriptomic signature and its medial layer: Implications in osteoarthritis., PMID:40462979
Xanthosomes loaded with recombinant TMEM219 for targeting IGFBP-3: A novel approach for targeted drug delivery to ameliorate liver fibrosis., PMID:40447257
Splice‑site variant c.3531+1G>T in COL1A1 in a family with osteogenesis imperfecta., PMID:40444480
Example of Intrafamilial Clinical Polymorphism in a Family with Osteogenesis Imperfecta., PMID:40428297
The Characterization of Serum-Free Media on Human Mesenchymal Stem Cell Fibrochondrogenesis., PMID:40428164
In vivo FAP-CAR macrophages enhance chemotherapy and immunotherapy against pancreatic cancer by removing the fibrosis barrier., PMID:40425095
C/EBPα mediates UVA-induced MMP1 overexpression in a histone H3 acetylation-dependent manner during skin photoaging., PMID:40417889
Peripheral Choroid/RPE/Sclera as a Shared Pathogenic Hub: Multi-Tissue Transcriptomic Profiling Identifies Common Differentially Expressed Genes in Age-Related Macular Degeneration and Alzheimer's Disease., PMID:40411685
Stress exposure affects amyotrophic lateral sclerosis pathogenesis via PI3K/Akt and focal adhesion pathways: evidence from three experimental models., PMID:40399476
A diet-driven metabolic dysfunction-associated steatohepatitis (MASH) mouse model resembles the corresponding human disease., PMID:40392411
Mesenchymal stem cell exosomes regulate TGFβ/Smad3 by decreasing the METTL3-NEAT1 axis to inhibit scar progression after breast surgery., PMID:40392368
POSTN Silencing Ameliorates LL37-Induced Rosacea and Inhibits the JAK2/STAT3 and NF-κB Pathways., PMID:40387439
Targeting Tumor Differentiation Grade-related Genes Prognostic Signature Including COL5A1 Based on Single-cell RNA-seq in Gastric Cancer., PMID:40386054
Investigating the Mechanism of the Fuzheng Huayu Formula in Treating Cirrhosis through Network Pharmacology, Molecular Docking, and Experimental Verification., PMID:40385224
Calprotectin inhibition attenuates silica-induced lung fibrosis., PMID:40381145
Osteogenesis imperfecta type V: About a clinical case., PMID:40379599
Blood biochemical landscape and new insights into clinical decision-making for polycystic ovary syndrome in Chinese women: a prospective cohort study., PMID:40375948
Harnessing the potential of recombinant human BMP2: regulating scleral changes in myopic guinea pigs., PMID:40375931
Anti-TGF-β treatment shows increased bone mass and strength in a novel mouse model for osteogenesis imperfecta type I., PMID:40358008
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration., PMID:40356987
TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515
[UPLC-Q-TOF-MS combined with network pharmacology reveals effect and mechanism of Gentianella turkestanorum total extract in ameliorating non-alcoholic steatohepatitis]., PMID:40350886
Licochalcone B attenuates pulmonary fibrosis via inhibiting ZBP1-dependent PANoptosis., PMID:40350052
Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180
[Construction of mouse podocyte clone-5 cell lines with Smad3 knockout by CRISPR/Cas9]., PMID:40328723
Gene Variants and Bisphosphonates Treatment in Pregnancy and Lactation-Associated Osteoporosis (PLO): A Retrospective Study of 22 Chinese Patients., PMID:40327138
Bone marrow mesenchymal stem cells alleviate liver fibrosis after rat liver transplantation through JAK1/STAT5 pathway., PMID:40312752
Genkwanin blocks the interaction between phosphorylated JNK and NFATc1 to promote osteogenic differentiation and collagen Ⅰ α1 production., PMID:40311832
Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness., PMID:40304034
Single-cell transcriptome unveils mesenchymal cell diversity in endometriosis., PMID:40302519
Antioxidant Potential of Gallic Acid Prevents Di-2-ethyhexyl Phthalate-induced Inhibition of Osteogenic Differentiation., PMID:40296616
Histamine H1 Receptor: A potential therapeutic target for pancreatic ductal adenocarcinoma., PMID:40288207
Effects of Botulinum Toxin A on Condylar Subchondral Bone Mass., PMID:40287806
Proteomic Analysis and 2-Hydroxyisobutyrylation Profiling in Metabolic Syndrome Induced Restenosis., PMID:40287094
Unravelling Paclitaxel Resistance in Gastric Cancer: The Role of Small Extracellular Vesicles in Epithelial Mesenchymal Transition and Extracellular Matrix Remodelling., PMID:40282535
LINC01711 modulates proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts by targeting miR-34a-5p., PMID:40278926
A human-ACE2 knock-in mouse model for SARS-CoV-2 infection recapitulates respiratory disorders but avoids neurological disease associated with the transgenic K18-hACE2 model., PMID:40272151
LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway., PMID:40264197
For research use only. Not for human or drug use.
