Catalog No.
YHD74901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly111-Leu228
Predicted molecular weight
15.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27701
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD82 antigen, C33 antigen, IA4, Inducible membrane protein R2, Metastasis suppressor Kangai-1, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, Tspan-27, CD82, CD82, KAI1, SAR2, ST6, TSPAN27
Impact of Tobacco Consumption on Salivary Protein Profiles: A MALDI-TOF Mass Spectrometry Study., PMID:40439360
Integration of Transcriptomic and Single-Cell Data to Uncover Senescence- and Ferroptosis-Associated Biomarkers in Sepsis., PMID:40299574
The untold story of CD82: Exploring its non-canonical roles in cancer., PMID:40252385
Upregulation of ferroptosis in glucocorticoids-induced posterior subcapsular cataracts., PMID:40234585
Augmentation of antiviral immune response induced by perturbation of CD82 under microgravity condition., PMID:39986582
Identification of biomarkers and mechanism exploration of ferroptosis related genes regulated by m6A in type 2 diabetes mellitus., PMID:39966875
Role of the transmembrane polar residues on CD151 in cholesterol binding., PMID:39743780
Transcriptomic integration and ligand-receptor crosstalk reveal the underlying molecular mechanisms between hip cartilage and subchondral bone in osteonecrosis of femoral head., PMID:39708930
A novel multiple marker microarray analyzer and methodology to predict major obstetric syndromes using surface markers of circulating extracellular vesicles from maternal plasma., PMID:39607297
Anti-metastatic Effects of Bee Venom and Melittin in Breast Cancer Cells by Upregulation of BRMS1 and DRG1 Genes., PMID:39396919
Overexpression of REC8 induces aberrant gamete meiotic division and contributes to AML pathogenesis - a multiplexed microarray analysis and mendelian randomization study., PMID:39012516
DNA Hypermethylation Inhibits the CD82 Metastasis Suppressor Gene in Gastric Cancer., PMID:38821592
Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3'UTR to decrease the expression of CD82., PMID:38765115
Evaluating the effects of various ethanolic medicinal plant extracts on metastatic breast cancer proliferation, invasion, and expression of a novel potential drug target; CD82 metastatic suppressor protein, and on in vivo angiogenesis using the ex ovo yolk sac membrane (YSM) assay., PMID:38753184
Plasma-derived extracellular vesicles improve mice embryo development., PMID:38709430
Characterization and LC-MS/MS based proteomic analysis of extracellular vesicles separated from blood serum of healthy and dogs naturally infected by Babesia canis. A preliminary study., PMID:38653059
A Potential Role of CD82/KAI1 during Uterine Decidualization in Mice., PMID:38534734
CD81 and CD82 expressing tumor-infiltrating lymphocytes in the NSCLC tumor microenvironment play a crucial role in T-cell activation and cytokine production., PMID:38515751
Tetraspanin CD82 Correlates with and May Regulate S100A7 Expression in Oral Cancer., PMID:38473906
The role of Tetraspanins in digestive system tumor development: update and emerging evidence., PMID:38389703
Hyperthermic shift and cell engineering increase small extracellular vesicle production in HEK293F cells., PMID:38037755
Broad-spectrum metastasis suppressing compounds and therapeutic uses thereof in human tumors., PMID:37990044
HTLV-1 biofilm polarization maintained by tetraspanin CD82 is required for efficient viral transmission., PMID:37889017
Quantitative proteomic analysis of local and systemic extracellular vesicles during Eimeria falciformis infectious cycle in the host., PMID:37759313
Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains., PMID:37736044
Quantitative analysis of soluble costimulatory molecules as potential diagnostic biomarkers for rheumatoid arthritis using LC-MS/MS in MRM mode., PMID:37516334
Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin., PMID:37434585
Liprin-α1 Expression in Tumor-Infiltrating Lymphocytes Associates with Improved Survival in Patients with HPV-Positive Oropharyngeal Squamous Cell Carcinoma., PMID:37335526
Prospective screening for δ-hemoglobinopathies associated with decreased hemoglobin A2 levels or hemoglobin A2 variants: A single center experience., PMID:37276945
Circadian Oscillation Pattern of Endoplasmic Reticulum Quality Control (ERQC) Components in Human Embryonic Kidney HEK293 Cells., PMID:37033333
Characterization and Proteomic Analysis of Plasma EVs Recovered from Healthy and Diseased Dogs with Canine Leishmaniosis., PMID:36982564
Recombinant human KAI1/CD82 attenuates M1 macrophage polarization on LPS-stimulated RAW264.7 cells via blocking TLR4/JNK/NF-κB signal pathway., PMID:36945827
Identification of Hub Genes Associated with Resistance to Prednisolone in Acute Lymphoblastic Leukemia Based on Weighted Gene Co-expression Network Analysis., PMID:36877306
Efficient Muscle Regeneration by Human PSC-Derived CD82+ ERBB3+ NGFR+ Skeletal Myogenic Progenitors., PMID:36766703
Inhibition of CD82 improves colitis by increasing NLRP3 deubiquitination by BRCC3., PMID:36600050
Potential diagnostic of lymph node metastasis and prognostic values of TM4SFs in papillary thyroid carcinoma patients., PMID:36568979
Extracellular Vesicles as Mediators of Nickel-Induced Cancer Progression., PMID:36555753
Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia., PMID:36315912
Distribution of tetraspanins in bovine ovarian tissue and fresh/vitrified oocytes., PMID:36242635
Isolation of a cytolytic subpopulation of extracellular vesicles derived from NK cells containing NKG7 and cytolytic proteins., PMID:36189227
The identification of novel small extracellular vesicle (sEV) production modulators using luciferase-based sEV quantification method., PMID:38938770
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer., PMID:36116374
Single-cell phenotypic profiling to identify a set of immune cell protein biomarkers for relapsed and refractory diffuse large B cell lymphoma: A single-center study., PMID:36040107
Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients., PMID:35979935
A Systematic Review of Circulating Tumor Cells Clinical Application in Prostate Cancer Diagnosis., PMID:35954464
Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations., PMID:35947128
Lower expression of KAI1 as a biomarker of poor survival prognosis of melanoma combined with colorectal cancer metastasis., PMID:35942551
Th2-Biased Transcriptional Profile Predicts HIV Envelope-Specific Polyfunctional CD4+ T Cells That Correlated with Reduced Risk of Infection in RV144 Trial., PMID:35803696
A subset of macrophages and monocytes in the mouse bone marrow express atypical chemokine receptor 1., PMID:35803223
Identification of Key Genes as Early Warning Signals of Acute Myocardial Infarction Based on Weighted Gene Correlation Network Analysis and Dynamic Network Biomarker Algorithm., PMID:35795669