Catalog No.
YHB95801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu22-Gln240
Predicted molecular weight
40.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01589
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA
Genetically predicted immune cells mediates the association between hepatocellular carcinoma and inflammatory proteins: a Mendelian randomization study., PMID:40504445
PD-1 Regulates the Glycolytic Pathway to Reverse Abnormal CD4+ T Cell Differentiation and Alleviate Hashimoto's Thyroiditis., PMID:40503724
A Case of High-Risk Myelodysplastic Syndrome With Cryoglobulinemia, Hemophagocytic Lymphohistiocytosis, and Progression to Multiple Organ Failure., PMID:40503540
Increase of CD4+CD25+FoxP3+Regulatory T Cells in Myeloma., PMID:40497604
An evaluation of denileukin diftitox for the treatment of relapsed or refractory cutaneous T-cell lymphoma., PMID:40489974
Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805
Impact of immune checkpoint TIGIT on the activation and function of natural killer cells in rheumatoid arthritis patients., PMID:40465407
Associations among IL-6 Signaling Molecules in Treg Populations in Patients with Relapsing-Remitting Multiple Sclerosis., PMID:40464469
Black Death protective gene mutation shows ambiguous role in type 1 diabetes, its complications, and common viral infections., PMID:40449626
Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species., PMID:40448101
Compensatory mechanisms in γδ T cell-deficient chickens following Salmonella infection., PMID:40438105
Asymmetric Dimethylarginine Disrupts Tumor Antigen Presentation in Breast Cancer., PMID:40429627
CD19+IL-10+ regulatory B cells induced by IL-12p35 regulates functional T-cell subsets in patients with immune thrombocytopenia., PMID:40415408
Rejuvenation of thymus and modulation of local and systemic T cell responses in animal model of Alzheimer's disease following cell therapy using sperm head., PMID:40409106
Streptococcal pyrogenic exotoxin a induces regulatory T cells via TNF-α-TNFR2 signaling., PMID:40402252
Prognostic Significance of Regulatory CD25+ T Cells in Bladder Cancer: An Immunohistochemical Analysis., PMID:40396924
Immunomodulatory effects of Eimeria maxima surface antigen (EmSAG) as an IFN-γ inhibitory molecule on peripheral blood mononuclear cells (PBMCs) and T cell subsets in chickens., PMID:40390138
Peripheral Immune-Inflammatory Parameters in Parkinson's Disease. Dependence on the Stage of Progression., PMID:40367079
Regulatory T cells suppress TLR9-induced formation of intrahepatic myeloid-cell aggregates for T cell population expansion in liver., PMID:40366446
Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381
Development and validation of an early diagnosis model for severe mycoplasma pneumonia in children based on interpretable machine learning., PMID:40361124
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD., PMID:40360083
IDO can improve ovarian function in premature ovarian insufficiency via AhR and regulatory T cells., PMID:40358004
Effects of albumin-bound paclitaxel combined with Sophora subprostrate polysaccharide on inflammatory factors and immune function in breast cancer rats., PMID:40347365
Schistosoma japonicum cystatin attenuated CLP-induced sepsis in mice though inducing tolerogenic dendritic cells and regulatory T cells., PMID:40344985
An elevated percentage of CD4⁺CD25⁺CD127low regulatory T cells in peripheral blood indicates a poorer prognosis in hepatocellular carcinoma after curative hepatectomy., PMID:40335903
Role of Stromal CD25+/CD8+ Lymphocyte Ratio in Patients With Grade 2-3 Cervical Intraepithelial Neoplasia (CIN 2-3): A Retrospective Single-center Study., PMID:40295043
Hyper-reactivity of CD8+ T cells and high expression of IL-3 correlates with occurrence and severity of Long-COVID., PMID:40287027
Elucidation of Desensitization Mechanisms Induced by Oral Immunotherapy in a Rat Model of Ovalbumin Allergy., PMID:40282825
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies., PMID:40280128
Ruxolitinib stopped before transplantation does not induce cytokine release in myelofibrosis., PMID:40274649
Soluble CD8 and CD25 along with anti-tTG autoantibody as non-invasive prognostic factor in celiac patients., PMID:40272918
Enhanced efficacy of dual chimeric antigen receptor-T cells targeting programmed death-ligand 1 and cancer-associated fibroblasts in colorectal cancer in vitro., PMID:40260068
Prospective analysis of the number and function of two T regulatory cell subsets in healthy individuals., PMID:40259466
Repeated Gonadotropin Administration Suppresses T Cell Development in the Mouse Thymus., PMID:40256124
Transient intracellular expression of PD-L1 and VEGFR2 bispecific nanobody in cancer cells inspires long-term T cell activation and infiltration to combat tumor and inhibit cancer metastasis., PMID:40253320
GPER1-mediated suppression of acute cellular rejection in murine cervical heart transplantation by estradiol., PMID:40247327
Lidocaine Modulates Cytokine Production and Reprograms the Tumor Immune Microenvironment to Enhance Anti-Tumor Immune Responses in Gastric Cancer., PMID:40244064
Enhancement of NK Cell Cytotoxic Activity and Immunoregulatory Effects of a Natural Product Supplement Across a Wide Age Span: A 30-Day In Vivo Human Study., PMID:40243481
Multiparametric Profiling of Circulating Immune Cells Identifies an Expansion of CD25high Switched Memory B Cells in Osteoarthritis., PMID:40229860
Exosomes from Tregs mitigate lung damage caused by smoking via inhibiting inflammation and altering T lymphocyte subsets in COPD rats., PMID:40229730
Autoantigen and IL-2 activated CD4+CD25+T regulatory cells are induced to express CD8 and are autoantigen specific in inhibiting experimental autoimmune encephalomyelitis., PMID:40228404
Role of Regulatory T Cells in Chronic Obstructive Pulmonary Disease., PMID:40226513
Quantitative Assessment of T-Regulatory Cell Population and FOXP3 Gene Expression in Chronically Exposed Residents of the Urals Region., PMID:40216726
CD4+CD25- T-Cell-Secreted IFN-γ Promotes Corneal Nerve Degeneration in Diabetic Mice., PMID:40192636
Phlorizin attenuates lupus nephritis via upregulating PI3K/Akt pathway-mediated Treg differentiation., PMID:40186900
The role of prostanoids in regulatory T cells and their implications in inflammatory diseases and cancers., PMID:40184828
Investigating the therapeutic potential of tryptophan and vitamin A in modulating immune responses in celiac disease: an experimental study., PMID:40178602
Markers of T Lymphocyte Activation in Children With Kawasaki Disease: An Experimental Study From North India., PMID:40143619
Comparison of Regulatory T-Cell Subpopulations in Antithymocytic Globulin Versus Post-Transplant Cyclophosphamide for Preventing Graft-Versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplantation-A Retrospective Study., PMID:40141165
For research use only. Not for human or drug use.
