Catalog No.
EVV27602
Expression system
Mammalian Cells
Species
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Protein length
Asn17-Thr204
Predicted molecular weight
49.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q89501
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD2 homolog, CD2H, 5HL, CD2v, T-lymphocyte CD2 receptor-like protein, CD2-like protein, pEP402R, Ba71V-058, EP402R
Development and efficacy of a novel mRNA cocktail for the delivery of African swine fever virus antigens and induction of immune responses., PMID:40298440
Characterization of African swine fever virus in Angola, 2024., PMID:40131561
Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface., PMID:40092189
A triple protein-based ELISA for differential detection of ASFV antibodies., PMID:39723184
From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes., PMID:39688401
How Does African Swine Fever Virus Evade the cGAS-STING Pathway?, PMID:39599510
A plant-based oligomeric CD2v extracellular domain antigen exhibits equivalent immunogenicity to the live attenuated vaccine ASFV-G-∆I177L., PMID:39412651
Protection Evaluation of a New Attenuated ASFV by Deletion of the L60L and CD2v Genes against Homologous Challenge., PMID:39339941
Towards Safe African Swine Fever Vaccines: The A137R Gene as a Tool to Reduce Virulence and a Promising Serological DIVA Marker Candidate., PMID:39272254
Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus., PMID:38846950
Preparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein., PMID:38734611
Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies., PMID:38588947
Generation and Characterization of Recombinant Pseudorabies Virus Delivering African Swine Fever Virus CD2v and p54., PMID:38203508
A Robust Quadruple Protein-Based Indirect ELISA for Detection of Antibodies to African Swine Fever Virus in Pigs., PMID:38004769
The CD2v protein of African swine fever virus inhibits macrophage migration and inflammatory cytokines expression by downregulating EGR1 expression through dampening ERK1/2 activity., PMID:37968713
A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response., PMID:37964304
A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein., PMID:37781934
Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus., PMID:37768082
Mucosal and cellular immune responses elicited by nasal and intramuscular inoculation with ASFV candidate immunogens., PMID:37720232
Mammalian Cell-Line-Expressed CD2v Protein of African Swine Fever Virus Provides Partial Protection against the HLJ/18 Strain in the Early Infection Stage., PMID:37515155
A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine., PMID:37401832
Deletion of the CD2 Gene in the Virulent ASFV Congo Strain Affects Viremia in Domestic Swine, but Not the Virulence., PMID:37370512
An Intracellular Epitope of ASFV CD2v Protein Elicits Humoral and Cellular Immune Responses., PMID:37370477
Subsequent Immunization of Pigs with African Swine Fever Virus (ASFV) Seroimmunotype IV Vaccine Strain FK-32/135 and by Recombinant Plasmid DNA Containing the CD2v Derived from MK-200 ASFV Seroimmunotype III Strain Does Not Protect from Challenge with ASFV Seroimmunotype III., PMID:37243111
Evaluation of humoral and cellular immune responses induced by a cocktail of recombinant African swine fever virus antigens fused with OprI in domestic pigs., PMID:37237390
African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication., PMID:37022174
African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways., PMID:36971697
ASFV proteins presented at the surface of T7 phages induce strong antibody responses in mice., PMID:36965632
Dynamics of Serological and Mucosal Antibody Responses against African Swine Fever Viruses in Experimentally Infected Pigs., PMID:40303747
Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam., PMID:36779206
Identification of a linear B-cell epitope on the African swine fever virus CD2v protein., PMID:36706875
Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies., PMID:36680174
Development and characterization of monoclonal antibodies against the extracellular domain of African swine fever virus structural protein, CD2v., PMID:36466651
Expression of extracellular domain of ASFV CD2v protein in mammalian cells and identification of B cell epitopes., PMID:36356676
Development of an indirect ELISA for the identification of African swine fever virus wild-type strains and CD2v-deleted strains., PMID:36157191
Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine., PMID:36146830
Host Responses to Live-Attenuated ASFV (HLJ/18-7GD)., PMID:36146810
Flow cytometry-based multiplexing antibody detection for diagnosis of African swine fever virus., PMID:36038241
Development of an ELISA Method to Differentiate Animals Infected with Wild-Type African Swine Fever Viruses and Attenuated HLJ/18-7GD Vaccine Candidate., PMID:36016353
First Report of a Complete Genome Sequence of a Variant African Swine Fever Virus in the Mekong Delta, Vietnam., PMID:35890041
Comparison of mucosal immune responses to African swine fever virus antigens intranasally delivered with two different viral vectors., PMID:35849881
African Swine Fever Virus Hemadsorption Inhibition Assay., PMID:35575893
Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody., PMID:35358580
Identification of Linear B Cell Epitopes on CD2V Protein of African Swine Fever Virus by Monoclonal Antibodies., PMID:35311572
Differential diagnosis of the infection caused by wild-type or CD2v-deleted ASFV strains by quantum dots-based immunochromatographic assay., PMID:35255156
Live pig markets are hotspots for spread of African swine fever virus in Nigeria., PMID:35179830
Molecular characterization of African swine fever viruses from Burkina Faso, 2018., PMID:35151326
In silico analysis of highly conserved cytotoxic T-cell epitopes in the structural proteins of African swine fever virus., PMID:34903918
The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β., PMID:34835302
Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)-Peptide Tetramers., PMID:34835070
For research use only. Not for human or drug use.
