Catalog No.
EHE14002
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His205
Predicted molecular weight
48.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35613
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Hepatoma-associated antigen, HAb18G, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG, UNQ6505/PRO21383
Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma-A Functional Link to Phenotype Heterogeneity., PMID:40508207
Correlation between ultrasound measurements and the expression of Her-2 and CD147 in breast cancer., PMID:40385050
Serum EMMPRIN/CD147 promotes the lung pre-metastatic niche in a D2A1 mammary carcinoma mouse model., PMID:40370456
CD147 inhibition reduced fibronectin expression in TGF-β1-induced keloid fibroblasts by targeting Smad2 signaling pathway., PMID:40319830
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells., PMID:40254691
Meplazumab, a CD147 antibody, for severe COVID-19: a double-blind, randomized, placebo-controlled, phase 3 clinical trial., PMID:40222976
Phillyrin from Forsythia suspensa suppresses the proliferation, angiogenesis, and metastasis of colorectal cancer via targeting CD147., PMID:40210179
CD147-CAR-NK cell therapy shows minimal toxicities in human CD147 transgenic mouse model with solid tumors., PMID:40160933
EMMPRIN Correlated with β-CATENIN in Various t Stages of Colorectal Adenocarcinoma., PMID:40156418
Urinary Basigin/CD147 is a useful marker of acute T cell-mediated rejection in kidney transplant recipients., PMID:40125925
CD147 Mediates the Metabolic Reprogramming of Cancer Associated Fibroblasts Induced by EVs Released by Differentiating Cancer Stem Cells., PMID:40104175
3-Hydroxybutyrate Promotes Myoblast Proliferation and Differentiation through Energy Metabolism and GPR109a-Mediated Ca2+-NFAT Signaling Pathways., PMID:40099866
Expression of MMP-14 and CD147 in Gingival Tissue of Patients With and Without Diabetes Mellitus Type II., PMID:40075856
An Anti-CD147 Antibody-Drug Conjugate Mehozumab-DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey., PMID:39985225
Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8., PMID:39963132
iPSC-derived human cortical organoids display profound alterations of cellular homeostasis following SARS-CoV-2 infection and Spike protein exposure., PMID:39950320
In vitro expression of genes encoding HIF1α, VEGFA, PGE2 synthases, and PGE2 receptors in feline oral squamous cell carcinoma., PMID:39930728
PPIA enhances cell growth and metastasis through CD147 in oral cancer., PMID:39921142
Early Use of Liraglutide for the Treatment of Acute COVID-19 Infection: An Open-Label Single-Center Phase II Safety Study with Biomarker Profiling., PMID:39846709
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy., PMID:39740799
Basigin in cerebrovascular diseases: Roles, mechanisms, and therapeutic target potential., PMID:39734038
RNA-binding protein HuR regulates the transition of septic AKI to CKD by modulating CD147., PMID:39716463
The mitochondrial lactate oxidation complex: endpoint for carbohydrate carbon disposal., PMID:39714986
Cell membrane chromatography relative competitive method for the accurate determination of relative KD values of drug-receptor interactions., PMID:39658753
Targeting autophagy in HCC treatment: exploiting the CD147 internalization pathway., PMID:39627812
[Analysis of Endogenous Metabolite Transporters for the Development of Novel Pharmaceutical Therapies and Drug Targets]., PMID:39617467
Disruption of the Physical Interaction Between Carbonic Anhydrase IX and the Monocarboxylate Transporter 4 Impacts Lactate Transport in Breast Cancer Cells., PMID:39596062
Galectin-3 disrupts tight junctions of airway epithelial cell monolayers by inducing expression and release of matrix metalloproteinases upon influenza A infection., PMID:39569730
CD147 expression as a clinicopathological and prognostic indicator in breast cancer: a meta-analysis and bioinformatics analysis., PMID:39567919
Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer., PMID:39549046
Adhesin RadD: the secret weapon of Fusobacterium nucleatum., PMID:39520704
Cyclophilin A knockdown inhibits the proliferation and metastatic ability of AGS gastric cancer stem cells by downregulating CD147/STAT3/AKT/ERK and epithelial‑mesenchymal transition., PMID:39513611
Cyclophilin A: promising target in cancer therapy., PMID:39513594
Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway., PMID:39475905
DMF-Bimol: Counting mRNA and Protein Molecules in Single Cells with Digital Microfluidics., PMID:39428609
Expression of nuclear receptors and glucose metabolic pathway proteins in sebaceous carcinoma: Androgen receptor and monocarboxylate transporter 1 have a key role in disease progression., PMID:39421321
Engineering affinity of humanized ScFv targeting CD147 antibody: A combined approach of mCSM-AB2 and molecular dynamics simulations., PMID:39405982
Cellular and extracellular proteomic profiling of paradoxical low-flow low-gradient aortic stenosis myocardium., PMID:39355352
Effects of atorvastatin and ezetimibe on CD147, HIF-1, MMP-2 and VEGF in carotid atherosclerotic plaque under the guidance of IVUS., PMID:39348642
The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19., PMID:39273582
Metabolic Function and Therapeutic Potential of CD147 for Hematological Malignancies: An Overview., PMID:39273126
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system., PMID:39218301
The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis., PMID:39169124
Receptors Involved in COVID-19-Related Anosmia: An Update on the Pathophysiology and the Mechanistic Aspects., PMID:39126095
Scalable process development of NK and CAR-NK expansion in a closed bioreactor., PMID:39114666
The binding of extracellular cyclophilin A to ACE2 and CD147 triggers psoriasis-like inflammation., PMID:39096717
Effects of SARS-COV-2 on molecules involved in vascularization and autophagy in placenta tissues., PMID:39088116
Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations., PMID:39080396
Inhibition of YIPF2 Improves the Vulnerability of Oligodendrocytes to Human Islet Amyloid Polypeptide., PMID:39078594
Rabenosyn-5 suppresses non-small cell lung cancer metastasis via inhibiting CDC42 activity., PMID:39075137
For research use only. Not for human or drug use.
