Catalog No.
RHC93501
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32, FCG2, FCGR2A1, IGFR2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P12318
Applications
Blocking, ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2150
A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015
FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs., PMID:40089806
The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity., PMID:39962623
Antibody-Dependent Cellular Cytotoxicity of iPS Cell-Derived Natural Killer T Cells by Anti-GD2 mAb for Neuroblastoma., PMID:39916425
C-reactive protein promotes diabetic kidney disease via Smad3-mediated NLRP3 inflammasome activation., PMID:39539016
Characterising how a single bout of exercise in people with myeloma affects clonal plasma cell and immune effector cell frequency in blood, and daratumumab efficacy in vitro., PMID:39411424
Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis., PMID:39342827
Systematic analysis of Fc mutations designed to enhance binding to Fc-gamma receptors., PMID:39306747
Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors., PMID:39279104
IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma., PMID:38585888
Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells., PMID:38579727
Control of complement-induced inflammatory responses to SARS-CoV-2 infection by anti-SARS-CoV-2 antibodies., PMID:38418557
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis., PMID:38391367
A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis., PMID:38375189
Type 2-polarized memory B cells hold allergen-specific IgE memory., PMID:38324637
Anti-Vα24Jα18 TCR Antibody Tunes iNKT Cell Responses to Target and Kill CD1d-negative Tumors in an FcγRII (CD32)-dependent Manner., PMID:38319156
Fc-gamma receptor expression and cytokine responses to intravenous human immunoglobulin in whole blood from non-pregnant and pregnant women and newborns., PMID:38180331
Nasal polyp antibody-secreting cells display proliferation signature in aspirin-exacerbated respiratory disease., PMID:37898408
High levels of PD-L1 on platelets of NSCLC patients contributes to the pharmacological activity of Atezolizumab., PMID:37857253
Developmental adaptations of γδ T cells and B cells in blood and intestinal mucosa from birth until weaning in Holstein bull calves., PMID:37806632
Macrophage N-glycan processing inhibits antibody-dependent cellular phagocytosis., PMID:37792857
Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes., PMID:37790943
DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection., PMID:37639455
Role of C-Reactive Protein in Kidney Diseases., PMID:37065607
A 16-color full spectrum flow cytometric analysis for comprehensive evaluation of T-cell reconstitution in SIV-infected rhesus macaques., PMID:36496008
Direct Binding of Bovine IgG-Containing Immune Complexes to Human Monocytes and Their Putative Role in Innate Immune Training., PMID:36364714
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer., PMID:36324077
Relationship between neutralizing and opsonizing monoclonal antibodies against foot-and-mouth disease virus., PMID:36311653
Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment., PMID:36241426
Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques., PMID:36167072
A cytotoxic effect of human lactoferrin fusion with Fc domain of IgG., PMID:36136256
Down-regulated FcγRII expression on plasma cells is associated with the disease activity of ANCA-associated vasculitis., PMID:36111855
Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality., PMID:35997348
Zika Virus Replication in a Mast Cell Model is Augmented by Dengue Virus Antibody-Dependent Enhancement and Features a Selective Immune Mediator Secretory Profile., PMID:35862953
Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response., PMID:35616530
Spontaneous Platelet Aggregation in Blood Is Mediated by FcγRIIA Stimulation of Bruton's Tyrosine Kinase., PMID:35008508
An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability., PMID:34687301
Immunoglobulin G Immune Complexes May Contribute to Neutrophil Activation in the Course of Severe Coronavirus Disease 2019., PMID:34398243
CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues., PMID:34220857
Systemic and mucosal mobilization of granulocyte subsets during lentiviral infection., PMID:34037988
Are Fc Gamma Receptor Polymorphisms Important in HIV-1 Infection Outcomes and Latent Reservoir Size?, PMID:34017334
Comparison of diagnostic performances of ten different immunoassays detecting anti-CCHFV IgM and IgG antibodies from acute to subsided phases of Crimean-Congo hemorrhagic fever., PMID:33720942
Platelet-activating immune complexes identified in critically ill COVID-19 patients suspected of heparin-induced thrombocytopenia., PMID:33639037
Genetic variation in the immune system and malaria susceptibility in infants: a nested case-control study in Nanoro, Burkina Faso., PMID:33593344
Cyclophosphamide alters the tumor cell secretome to potentiate the anti-myeloma activity of daratumumab through augmentation of macrophage-mediated antibody dependent cellular phagocytosis., PMID:33552684
Human peripheral basophils extended phenotype shows a high expression of CD244 immuno-regulatory receptor., PMID:33493550
Scleroderma-specific autoantibodies embedded in immune complexes mediate endothelial damage: an early event in the pathogenesis of systemic sclerosis., PMID:33168071
Basal Levels of CD18 Antigen Presenting Cells in Cow Milk Associate with Copy Number Variation of Fc Gamma Receptors., PMID:32824852
Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context., PMID:32678124
FcγRII (CD32) modulates antibody clearance in NOD SCID mice leading to impaired antibody-mediated tumor cell deletion., PMID:32554613
For research use only. Not for human or drug use.
