Catalog No.
RHF75402
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Target
CBX1, CBX, Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1 beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P83916
Applications
ELISA, IF, IP
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2129
Role of HP1β during spermatogenesis and DNA replication., PMID:32651609
Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT+ B-lymphoblastic leukemia/lymphoma., PMID:31776129
Engineered Reader Proteins for Enhanced Detection of Methylated Lysine on Histones., PMID:31634430
Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction., PMID:29464021
Intrabody-mediated diverting of HP1β to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor., PMID:26364738
CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage., PMID:26158765
Non-radioactive protein lysine methyltransferase microplate assay based on reading domains., PMID:23671032
Granulocyte maturation determines ability to release chromatin NETs and loss of DNA damage response; these properties are absent in immature AML granulocytes., PMID:23269287
Aurora kinase B activity is modulated by thyroid hormone during transcriptional activation of pituitary genes., PMID:21239609
Age-associated increase in heterochromatic marks in murine and primate tissues., PMID:21176091
DNA synthesis and epigenetic modification during mouse oocyte fertilization by human or hamster sperm injection., PMID:21107900
Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1., PMID:18590578
The heterochromatin protein 1 family is regulated in prostate development and cancer., PMID:18436254
Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting., PMID:16283356
Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance., PMID:15215892
Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase., PMID:12840071
HP1beta and HP1gamma, but not HP1alpha, decorate the entire XY body during human male meiosis., PMID:12675308
Pim-1 associates with protein complexes necessary for mitosis., PMID:12111331
Immunolocalization of HP1 proteins in metaphasic mammalian chromosomes., PMID:11741155
HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes., PMID:11124534
M31, a murine homolog of Drosophila HP1, is concentrated in the XY body during spermatogenesis., PMID:10516442
Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells., PMID:10460410
KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing., PMID:10330177
For research use only. Not for human or drug use.
