Catalog No.
PHJ51301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HDAC8 (Met1-Val377).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
HDAC8,Histone deacetylase 8,HD8,HDACL1
Purification
Purified by antigen affinity column.
Accession
Q9BY41
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the "Smart" exosome nanoparticle therapy., PMID:39004737
Histone deacetylase 8 inhibition suppresses mantle cell lymphoma viability while preserving natural killer cell function., PMID:33190829
HDAC8 inhibition ameliorates pulmonary fibrosis., PMID:30358439
Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells., PMID:29174371
Analysis of the interactome of Schistosoma mansoni histone deacetylase 8., PMID:29155817
HDAC inhibitors enhance the immunotherapy response of melanoma cells., PMID:29137331
Histone deacetylase inhibitors attenuate P-aIgA1-induced cell proliferation and extracellular matrix synthesis in human renal mesangial cells in vitro., PMID:26775659
Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo., PMID:25451941
Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity., PMID:25019367
Histone deacetylase 8 regulates cortactin deacetylation and contraction in smooth muscle tissues., PMID:24920679
Characterization of an antibody panel for immunohistochemical analysis of canine muscle cells., PMID:18617272
Novel smooth muscle markers reveal abnormalities of the intestinal musculature in severe colorectal motility disorders., PMID:16771768
Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells., PMID:15590418