Catalog No.
PHJ49001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human HEPH (Ala24-Cys366).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
HEPH,KIAA0698,Hephaestin
Purification
Purified by antigen affinity column.
Accession
Q9BQS7
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Immunoreactivities for hepcidin, ferroportin, and hephaestin in astrocytes and choroid plexus epithelium of human brains., PMID:31755170
An immunohistochemical study of placental syncytiotrophoblasts in neonatal hemochromatosis., PMID:27871472
Immunoreactive hephaestin and ferroxidase activity are present in the cytosolic fraction of rat enterocytes., PMID:22350470
Interactions between ferroportin and hephaestin in rat enterocytes are reduced after iron ingestion., PMID:21473866
Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells., PMID:20019163
Iron feeding induces ferroportin 1 and hephaestin migration and interaction in rat duodenal epithelium., PMID:18974313
Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD., PMID:18326691
Ferroportin1 and hephaestin are involved in the nigral iron accumulation of 6-OHDA-lesioned rats., PMID:17561842
Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells., PMID:17486601
Systemic regulation of Hephaestin and Ireg1 revealed in studies of genetic and nutritional iron deficiency., PMID:12730111
Cellular location of proteins related to iron absorption and transport., PMID:11891802
Iron absorption and transport., PMID:10522550
For research use only. Not for human or drug use.
