Anti-MYOC Polyclonal Antibody

Catalog No.

PHJ48001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MYOC (Ala224-Tyr471).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MYOC,Myocilin,Trabecular meshwork-induced glucocorticoid response protein,GLC1A,TIGR,Myocilin 55 kDa subunit,Myocilin 35 kDa N-terminal fragment,Myocilin 20 kDa N-terminal fragment

Purification

Purified by antigen affinity column.

Accession

Q99972

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

A proteomic approach towards understanding the pathogenesis of Mooren's ulcer., PMID:33647271

Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye., PMID:30906929

Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies., PMID:26121352

Complex genetic mechanisms in glaucoma: an overview., PMID:21150032

Efficient in vivo doxycycline and cre recombinase-mediated inducible transgene activation in the murine trabecular meshwork., PMID:21051732

Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma., PMID:18436825

Aqueous humor myocilin protein levels in normal, genetic carriers, and glaucoma Beagles., PMID:18435660

Immunohistochemical evaluation of the extracellular matrix in trabecular meshwork in steroid-induced glaucoma., PMID:18386038

Immunolocalization of myocilin protein in the anterior eye of normal and primary open-angle glaucomatous dogs., PMID:17973832

[Comparative study of eukaryotic cell expression of wild-type and Pro370Leu mutation type myocilin gene]., PMID:16681932

Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta., PMID:16303956

Protein expression, genomic structure, and polymorphisms of oculomedin., PMID:12868032

In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin., PMID:11773026

Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues., PMID:11431441

Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head., PMID:11344104

Immunohistochemical localization of MYOC/TIGR protein in the trabecular tissue of normal and glaucomatous eyes., PMID:11262617

Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment., PMID:11095610

Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye., PMID:11035548

Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor., PMID:10947851

Isolation, culture, and characterization of endothelial cells from Schlemm's canal., PMID:9727403

Localization of Dictyostelium myoB and myoD to filopodia and cell-cell contact sites using isoform-specific antibodies., PMID:8980908

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions., PMID:8609164

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