Catalog No.
DHB88402
Expression system
Mammalian Cells
Species reactivity
Human
Isotype
Recombinant tissue plasminogen activator (rt-PA) with C-terminal 6*His
Target
Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, 3.4.21.68, Alteplase, Reteplase, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, PLAT
Concentration
0.48 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P00750
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
20mM MES pH 6.0, 1mM CaCl2, 150mM NaCl, 0.01% Tween 80
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Alteplase
Prediction of outcomes following intravenous thrombolysis in patients with acute ischemic stroke using serum UCH-L1, S100β, and NSE: a multicenter prospective cohort study employing machine learning methods., PMID:40511467
Adjunctive intra-arterial thrombolysis after successful endovascular thrombectomy for large vessel occlusion: Meta-analysis of outcomes, dosage, and patient selection., PMID:40506219
Treatment outcomes in pediatric empyema: a retrospective observational study from a tertiary center in Dubai, United Arab Emirates., PMID:40504261
Early Drainage of Macula-Involving Massive Suprachoroidal Haemorrhage Assisted with Recombinant Tissue Plasminogen Activator May Lead to Better Visual Prognosis., PMID:40503215
Free Flap Salvage Using Extracorporeal Tissue Plasminogen Activator Administration: A Comparative Study., PMID:40502428
Enhancing Thrombolysis Safety in Post-Acute Ischemic Stroke with Tissue Plasminogen Activator-Associated Microparticles., PMID:40498863
Plasminogen supplementation improves lysis of inflammatory retained traumatic hemothorax., PMID:40497789
The dose of alteplase in massive pulmonary embolism: should it be individualized?, PMID:40494601
Investigation of the Influence of Lipoprotein(a) and Oxidized Lipoprotein(a) on Plasminogen Activation and Fibrinolysis., PMID:40492181
Thrombolysis in dysfunctional valve and stroke., PMID:40491881
Safety and Feasibility of Endovascular Management of Pediatric Dialysis Access., PMID:40490623
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress., PMID:40489346
Case Report: Does extracorporeal membrane oxygenation treatment for acute pulmonary embolism-induced respiratory and cardiac arrest still require thrombolysis?, PMID:40486829
Hip pain - an uncommon cause of extensive deep vein thrombosis (DVT) in the paediatric age group: a case report., PMID:40486006
Comparing fibrinolytic strategies in intermediate-high-risk pulmonary embolism: Insights from a multicenter registry., PMID:40483979
Hemoglobin decline within 24 h post-mechanical thrombectomy as an indicator of poor clinical outcomes., PMID:40483900
Letter to the editor, regarding "Transition from alteplase to tenecteplase for treatment of acute ischemic stroke in a rural stroke network of the Midwest: Planning, execution, safety, and outcomes" recently published by Loggini., PMID:40482545
Diagnostic value of Novel Thrombus Markers in COPD with Deep Venous Thrombosis., PMID:40480301
Intravenous Glyburide in Medical and Endovascular-Treated Large-Core Stroke: A Subgroup Analysis of the CHARM Randomized Clinical Trial., PMID:40476628
Association between adiposity distribution and high-sensitivity C-reactive protein, adipokines, interleukins and plasminogen activator inhibitor-1., PMID:40461792
[Effects of total extract of Anthriscus sylvestris on immune inflammation and thrombosis in rats with pulmonary arterial hypertension based on TGF-β1/Smad3 signaling pathway]., PMID:40461203
Targeting Neutrophil Extracellular Traps: A New Strategy for the Treatment of Acute Ischemic Stroke Based on Thrombolysis Resistance., PMID:40461018
The Non-Nutritive Sweetner Erythritol Adversely Affects Brain Microvascular Endothelial Cell Function., PMID:40459966
Novel Urokinase-Type Plasminogen Activator Receptor-Targeting Optical Imaging Agent ICG-Glu-Glu-AE105 for Visualization of Malignant Glioma During Surgery: First-in-Human Study in 35 Patients with Brain Cancer., PMID:40459950
Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation., PMID:40458179
Emergency anterior cerebral artery endarterectomy after mechanical thrombectomy failure: illustrative case., PMID:40456212
Production of a Recombinant Fibrinolytic Protease from an Isolate of Serratia marcescens from the Amazon Basin., PMID:40454077
Adjunctive intra-arterial thrombolysis after thrombectomy: Findings from the RITE registry., PMID:40452419
Tenecteplase in acute ischemic stroke: a new era in thrombolysis., PMID:40451189
Vascular Assessment in Adult Survivors of Childhood Cancer: A St. Jude Lifetime Cohort Study Report., PMID:40446733
Comparative efficacy of urokinase and recombinant tissue-type plasminogen activators in intraventricular hemorrhage., PMID:40445469
Intrapleural tissue plasminogen activator and deoxyribonuclease in complex pleural effusion and empyema, clinical outcomes, and predictors., PMID:40444335
Antiretroviral Therapy at Conception Leads to Lower Peripheral CD49a+ NK Cells and Higher SERPINB2., PMID:40438469
Managing Choroidal Neovascularization in Pseudoxanthoma Elasticum: Outcomes of Vitrectomy and Intravitreal Ranibizumab/Aflibercept Therapy-A Case Report., PMID:40438152
Safety and Long-Term Efficacy of Intravitreal rtPA, Bevacizumab and SF6 Injection in Patients with Submacular Hemorrhage Secondary to Age-Related Macular Degeneration., PMID:40429443
Treatment Strategies and Prognostic Outcomes in Acute Limb Ischemia: A Systematic Review and Meta-Analysis Comparing Thrombolytic Therapy and Open Surgical Interventions., PMID:40428785
Efficacy and Safety of Recombinant Human Prourokinase in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials., PMID:40426637
Use of alteplase continuous rate infusion, pentoxifylline, and cyproheptadine in association or not, in acute feline aortic thromboembolism: a study of nine cats., PMID:40420956
"Cilioretinal artery occlusion: Current scenario"., PMID:40420723
Predictive Model for Early Neurological Deterioration in Acute Ischemic Stroke Utilizing Novel Thrombotic Biomarkers., PMID:40418684
Unexpected Development of Pericardial Effusion in a Patient With Influenza and Secondary Bacterial Infection., PMID:40416904
Evaluating Signal Peptide Efficiency for Extracellular Protein Secretion for mRNA Vaccine Design., PMID:40414727
Dissolving porcine and human microthrombi by short exposure to microdoses of alteplase in an in vitro model of microvascular obstruction., PMID:40413305
Arterial collateral status and treatment effect of intravenous alteplase thrombolysis prior to endovascular treatment in patients with anterior circulation large vessel occlusion: prespecified analysis of the MR CLEAN-NO IV trial., PMID:40413026
Subretinal tissue plasminogen activator in polypoidal choroidal vasculopathy-related submacular haemorrhage and exudative retinal detachment., PMID:40409770
Impact of Telemedicine Adoption on Hemiplegia in Patients With Stroke in Florida: Longitudinal Observational Study., PMID:40409749
Enhancing thrombolysis efficiency using acoustic vortex tweezers and microbubbles: a microscale mechanistic study with experimental validation., PMID:40403337
Neuroprotective Mechanisms of Baicalin in Ischemia Stroke., PMID:40402033
Peripheral Blood Plasminogen Activator Inhibitor 1 and Tissue-Type Plasminogen Activator-Inhibitor Complex Levels for the Diagnosis and Prediction Value of Venous Thromboembolism in Malignant Tumors., PMID:40401695
Fibrinogen Depletion Coagulopathy and Hemorrhagic Transformation in Acute Ischemic Stroke Treated With Bridging Therapy., PMID:40400131
For research use only. Not for human or drug use.
