Catalog No.
DHD72204
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
CD27L receptor, TNFRSF7, T14, CD27 antigen, Tumor necrosis factor receptor superfamily member 7, CD27, T-cell activation antigen CD27
Concentration
2.51 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P26842
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
M2191
Monitoring anti-Rituximab antibodies in myasthenia gravis affects the time to event during Rituximab treatment., PMID:40488894
Adaptive immune changes in colorectal cancer: a focus on T and B cell activation genes., PMID:40484866
Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805
Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study., PMID:40442445
Interferon signatures fuel B cell hyperactivity and plasmablast expansion in systemic lupus erythematosus., PMID:40424895
The CD70-CD27 axis in cancer immunotherapy: Predictive biomarker and therapeutic target., PMID:40388162
Microbead-based synthetic niches for in vitro expansion and differentiation of human naïve B-cells., PMID:40385534
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics., PMID:40322080
Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity., PMID:40321757
Influence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia., PMID:40313965
CD70-Targeted [18F]RCCB6 Immuno-PET/CT Imaging in Patients with Nasopharyngeal Carcinoma: A Proof-of-Concept Study., PMID:40306966
Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial., PMID:40298406
The role of double-negative B cells in the pathogenesis of systemic lupus erythematosus., PMID:40274006
Desensitization With Proteasome Inhibition and Costimulation Blockade Modulates the Xenoreactive Humoral Response in Nonhuman Primate Xenotransplantation., PMID:40259710
Unsupervised machine learning identifies distinct systemic lupus erythematosus patient endotypes with differential response to belimumab., PMID:40244828
CD70 recruitment to the immunological synapse is dependent on CD20 in B cells., PMID:40232798
Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection., PMID:40222009
Long-lasting antibody B-cell responses to SARS-CoV-2 three years after the onset of the pandemic., PMID:40173043
Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection., PMID:40173042
Impact of Protein Kinase C Activation and Monoclonal Antibodies on Immune Checkpoint Regulation and B Cell Function in Patients with Chronic Lymphocytic Leukemia., PMID:40149717
Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients., PMID:40134233
Comprehensive Phenotyping and Cytokine Production of Circulating B Cells Associate Resting Memory B Cells With Early Antibody-mediated Rejection in Kidney Transplant Recipients., PMID:40124243
Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease., PMID:40078987
IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727
CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity., PMID:40046047
Development and Preclinical Evaluation of [64Cu]Cu-NOTA-ABDB6: A CD70 and Albumin Dual-Binding Tracer with Improved Pharmacokinetics., PMID:40015924
Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975
Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:39939347
Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase., PMID:39931747
BNT162b2 mRNA vaccination affects the gut microbiome composition of patients with follicular lymphoma and chronic lymphocytic leukemia., PMID:39930533
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept., PMID:39925810
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
Myricetin exposure reduces PC differentiation in vitro in primary human B cells., PMID:39875809
Maternal obesity associates with altered humoral immunity in blood and colostrum., PMID:39870213
Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis., PMID:39867643
The Role of Dendritic Cells in Adaptive Immune Response Induced by OVA/PDDA Nanoparticles., PMID:39852855
Bivalent OX40 Aptamer and CpG as Dual Agonists for Cancer Immunotherapy., PMID:39841045
Novel Sarcoidosis Epitope Augments MHCII, CD80/CD86 Expression, Promotes B-Cell Differentiation and IgG Production., PMID:39836049
Genetically reprogrammed exosomes for immunotherapy of acute myeloid leukemia., PMID:39815621
Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells., PMID:39812873
Longitudinal monitoring of class-switched memory-B cell proportions identifies plausible germinal center failure in patients with suspected immune disorders., PMID:39791256
Subset of DN Memory B Cells Expressing Low Levels of Inhibitory Receptor BTLA Is Enriched in SLE Patients., PMID:39768154
Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus., PMID:39740932
PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia., PMID:39733605
Donor HLA-DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21 low CD27 - B cells with high-avidity germline B-cell receptors., PMID:39713394
B Cell Receptor Repertoire Analysis of the CD21lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis., PMID:39707660
Herpesvirus Antibodies Are Correlated With Greater Expression of p16 in the T Cells of Humans., PMID:39703789
Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935
Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development., PMID:39687626