Catalog No.
YVV08902
Expression system
E. coli
Species
Human papillomavirus type 16
Protein length
Met1-Pro98
Predicted molecular weight
13.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03129
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein E7, E7
A novel Zn2+ probe for fluorescent monitoring of drug and E6/E7 protein interaction in living cells., PMID:40480729
Crosstalk Between the Oncoproteins of High-Risk Human Papillomaviruses Types 16 and 18 in Colorectal Cancer Cell Models., PMID:40468102
Therapeutic mRNA vaccines targeting human papillomavirus type 16 E7 protein demonstrate significant antitumor efficacy in murine models of HPV-associated tumors., PMID:40446873
A Luminescence-Based Method for In Vitro Screening of Immunomodulatory Checkpoints and Therapeutics., PMID:40402459
Zinc-alpha-2-glycoprotein overexpression and maintaining anti-apoptotic function in oral squamous cell carcinoma., PMID:40398100
Higher Expression of HPV16 Derived E7_LI Transcript Observed in Men With HIV and Recurrent Anal Cancer., PMID:40317526
Thymoquinone enhances efficacy of cervical Cancer therapeutic vaccines via modulating CD8+ T cells., PMID:40316484
HPV16 E7 inhibits HBD2 expression by down-regulation of ASK1-p38 MAPK pathway in cervical cancer., PMID:40253372
E7HPV16 Oncogene and 17beta-Estradiol Stress, Promotes Oncogenic microRNA Expression Patterns, Cell Proliferation and Cervical Intraepithelial Neoplasia 1., PMID:40114417
Metformin-induced E6/E7 inhibition prevents HPV-positive cancer progression through p53 reactivation., PMID:40100964
[Redox Status and Protein Glutathionylation in Binase-Treated HPV16-Positive SiHa Carcinoma Cells]., PMID:39970121
Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV., PMID:39958352
Immunization with recombinant HPV16-E7d in fusion with Flagellin as a cancer vaccine: Effect of antigen-adjuvant orientation on the immune response pattern., PMID:39939497
Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization., PMID:39910471
The combined immunization of cervical cancer therapeutic vaccine based on Listeria balanced lethal system has a significant therapeutic effect on tumor model mice., PMID:39870008
Oncoproteins E6/E7 of the human papillomavirus types 16 & 18 synergize in modulating oncogenes and tumor suppressor proteins in colorectal cancer., PMID:39815804
Roles of Mature Domain Targeting Signals (MTSs) for Protein Translocation and Secretion in Lactococcus lactis., PMID:39796073
Augmented immunogenicity of the HPV16 DNA vaccine via dual adjuvant approach: integration of CpG ODN into plasmid backbone and co-administration with IL-28B gene adjuvant., PMID:39780219
SLC7A11 Expression Is Up-Regulated in HPV- and Tobacco-Associated Lung Cancer., PMID:39769017
CRISPR/Cas14a integrated with DNA walker based on magnetic self-assembly for human papillomavirus type 16 oncoprotein E7 ultrasensitive detection., PMID:39764982
Designing of an mRNA vaccine against high-risk human papillomavirus targeting the E6 and E7 oncoproteins exploiting immunoinformatics and dynamic simulation., PMID:39761277
Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease., PMID:39751916
Comparative efficacy of HPV 16/18 DNA and E6/E7 mRNA testing in detecting high-grade cervical lesions (CIN2+) in women with cervical biopsies., PMID:39733635
Entropy-Driven Molecular Beacon Assisted Special RCA Assay with Enhanced Sensitivity for Room Temperature DNA Biosensing., PMID:39727883
[Amino Acid Substitution Patterns in the E6 and E7 Proteins of HPV Type 16: Phylogeography and Evolution]., PMID:39709561
LADS: a powerful vaccine platform for cancer immunotherapy and prevention., PMID:39696249
Upregulation of HPV16E1 and E7 expression and FOXO3a mRNA downregulation in high-grade cervical neoplasia., PMID:39655333
The HPV101 E7 protein shares host cellular targets and biological activities with high-risk HPV16 E7., PMID:39643241
STING Nanoagonist Boosts Antitumor Immunity of Therapeutic DNA Vaccines., PMID:39621441
Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen-processing-presentation machinery and poor patient survival., PMID:39619016
Human Papillomavirus Infection and Autoimmune Diseases: A Two-Sample Bidirectional Mendelian Randomization Study., PMID:39618109
Development of a magnetic α-Fe2O3/Fe3O4 heterogeneous nanorod-based electrochemical biosensing platform for HPV16 E7 oncoprotein detection., PMID:39603292
ELF3 Overexpression Contributes to the Malignant Transformation of HPV16 E6/E7-Immortalized Keratinocytes by Promoting CCNE2 Expression., PMID:39572025
LAMP-based electrochemical platform for monitoring HPV genome integration at the mRNA level associated with higher risk of cervical cancer progression., PMID:39420658
Detection of transcriptionally active high-risk human papillomavirus in patients with oesophageal carcinoma by real-time PCR., PMID:39412909
Recombinant adenoviruses expressing HPV16/18 E7 upregulate the HDAC6 and DNMT3B genes in C33A cells., PMID:39411320
HPV16 mutant E6/E7 construct is protective in mouse model., PMID:39350162
Epstein-Barr virus replication within differentiated epithelia requires pRb sequestration of activator E2F transcription factors., PMID:39291960
hnRNP H controls alternative splicing of human papillomavirus type 16 E1, E6, E7, and E6^E7 mRNAs via GGG motifs., PMID:39287390
The lncRNA and miRNA regulatory axis in HPV16-positive oropharyngeal cancers., PMID:39244802
HPV 16/18 E7 oncoprotein detection as a promising triage strategy for HPV 16/18-positive patients: A prospective multicenter study with a 2-year follow up., PMID:39244722
No genetic causal association between human papillomavirus and lung cancer risk: a bidirectional two-sample Mendelian randomization analysis., PMID:39227966
Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous TLR2/6 ligand derived from cysteinyl-tRNA synthetase 1., PMID:39066478
Differential tumor immune microenvironment coupled with tumor progression or tumor eradication in HPV-antigen expressing squamous cell carcinoma (SCC) models., PMID:39055715
Time to take HPV infection in colorectal cancer patients more seriously., PMID:39050539
Exosomal EGFR and miR-381-3P Mediate HPV-16 E7 Oncoprotein-Induced Angiogenesis of Non-Small Cell Lung Cancer., PMID:38812317
Exploring the Role of E6 and E7 Oncoproteins in Cervical Oncogenesis through MBD2/3-NuRD Complex Chromatin Remodeling., PMID:38790189
Design and evaluation of a multi-epitope DNA vaccine against HPV16., PMID:38780076
An E7-retinoblastoma protein pathway mechanism may account for the higher carcinogenic ability of HPV16 over HPV58 in cervical cancer., PMID:38737678
Development of an mRNA-based therapeutic vaccine mHTV-03E2 for high-risk HPV-related malignancies., PMID:38715363
For research use only. Not for human or drug use.
