Catalog No.
PHJ39201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NEIL1 (Ser43-Ala314).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Endonuclease 8-like 1,DNA glycosylase/AP lyase Neil1,Endonuclease VIII-like 1,Nei-like protein 1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Nei homolog 1,NEIL1,FPG1,NEH1
Purification
Purified by antigen affinity column.
Accession
Q96FI4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Development and characterization of a novel NEIL1 nanobody., PMID:40440929
Deciphering the crystal structure of a novel nanobody against the NEIL1 DNA glycosylase., PMID:38289715
Deciphering the orthorhombic crystal structure of a novel NEIL1 nanobody with pseudo-merohedral twinning., PMID:37609231
Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis., PMID:36749097
DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model., PMID:34186496
NEIL1 is a candidate gene associated with common variable immunodeficiency in a patient with a chromosome 15q24 deletion., PMID:28093361
Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA., PMID:26733197
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells., PMID:23405159
Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion., PMID:19782007
Human NEIL1 localizes with the centrosomes and condensed chromosomes during mitosis., PMID:17556049