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Anti-CTHRC1 Polyclonal Antibody

Catalog #:   PHJ38001 Specific References (26) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q96CG8
Overview

Catalog No.

PHJ38001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CTHRC1 (Ser31-Lys243).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Collagen triple helix repeat-containing protein 1,CTHRC1

Purification

Purified by antigen affinity column.

Accession

Q96CG8

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CTHRC1 antibody (PHJ38001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with CTHRC1 antibody (PHJ38001) at 1 μg/ml.

    Lane 1: Marker
    Lane 2: RT-4
    Lane 3: U251-MG

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human melanoma stained for CTHRC1 with PHJ38001.
References

Platelets modulate cardiac remodeling via the collagen receptor GPVI after acute myocardial infarction., PMID:38274818

CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)., PMID:37444482

Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis., PMID:36843438

CTHRC1 is a Potential Prognostic Biomarker and Correlated with Macrophage Infiltration in Breast Cancer., PMID:35755862

Application of collagen triple helix repeat containing-1 and mitotic spindle apparatus antibody in small cell lung cancer diagnosis., PMID:35385156

IgD promotes pannus formation by activating Wnt5A-Fzd5-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of IgD-Fc-Ig fusion protein., PMID:34688134

Cancer-associated fibroblast-secreted collagen triple helix repeat containing-1 promotes breast cancer cell migration, invasiveness and epithelial-mesenchymal transition by activating the Wnt/β-catenin pathway., PMID:34671428

CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer., PMID:33986509

Value of serum collagen triple helix repeat containing-1(CTHRC1) and 14-3-3η protein compared to anti-CCP antibodies and anti-MCV antibodies in the diagnosis of rheumatoid arthritis., PMID:32813981

TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex., PMID:31505254

CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis., PMID:31249576

Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling., PMID:30639416

Inhibition of CTHRC-1 by its specific monoclonal antibody attenuates cervical cancer cell metastasis., PMID:30554114

Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer., PMID:29021002

Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1., PMID:28115279

CTHRC1 promotes angiogenesis by recruiting Tie2-expressing monocytes to pancreatic tumors., PMID:27686285

Collagen triple helix repeat containing 1 is a new promigratory marker of arthritic pannus., PMID:27430622

Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumors., PMID:24945147

CTHRC1 acts as a prognostic factor and promotes invasiveness of gastrointestinal stromal tumors by activating Wnt/PCP-Rho signaling., PMID:24726140

Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling., PMID:23602936

Cthrc1, a novel circulating hormone regulating metabolism., PMID:23056600

Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer., PMID:22321245

Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis., PMID:22005949

Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study., PMID:21742751

Collagen triple helix repeat containing-1 in the differential diagnosis of dermatofibrosarcoma protuberans and dermatofibroma., PMID:20849518

Intracellular localization of Cthrc1 characterizes differentiated smooth muscle., PMID:18467647

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CTHRC1 Polyclonal Antibody [PHJ38001]
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