Catalog No.
PHJ38001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CTHRC1 (Ser31-Lys243).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Collagen triple helix repeat-containing protein 1,CTHRC1
Purification
Purified by antigen affinity column.
Accession
Q96CG8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Platelets modulate cardiac remodeling via the collagen receptor GPVI after acute myocardial infarction., PMID:38274818
CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)., PMID:37444482
Serum sirtuin-1 a potential marker in the diagnosis of rheumatoid arthritis., PMID:36843438
CTHRC1 is a Potential Prognostic Biomarker and Correlated with Macrophage Infiltration in Breast Cancer., PMID:35755862
Application of collagen triple helix repeat containing-1 and mitotic spindle apparatus antibody in small cell lung cancer diagnosis., PMID:35385156
IgD promotes pannus formation by activating Wnt5A-Fzd5-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of IgD-Fc-Ig fusion protein., PMID:34688134
Cancer-associated fibroblast-secreted collagen triple helix repeat containing-1 promotes breast cancer cell migration, invasiveness and epithelial-mesenchymal transition by activating the Wnt/β-catenin pathway., PMID:34671428
CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer., PMID:33986509
Value of serum collagen triple helix repeat containing-1(CTHRC1) and 14-3-3η protein compared to anti-CCP antibodies and anti-MCV antibodies in the diagnosis of rheumatoid arthritis., PMID:32813981
TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex., PMID:31505254
CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis., PMID:31249576
Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling., PMID:30639416
Inhibition of CTHRC-1 by its specific monoclonal antibody attenuates cervical cancer cell metastasis., PMID:30554114
Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer., PMID:29021002
Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1., PMID:28115279
CTHRC1 promotes angiogenesis by recruiting Tie2-expressing monocytes to pancreatic tumors., PMID:27686285
Collagen triple helix repeat containing 1 is a new promigratory marker of arthritic pannus., PMID:27430622
Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumors., PMID:24945147
CTHRC1 acts as a prognostic factor and promotes invasiveness of gastrointestinal stromal tumors by activating Wnt/PCP-Rho signaling., PMID:24726140
Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling., PMID:23602936
Cthrc1, a novel circulating hormone regulating metabolism., PMID:23056600
Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer., PMID:22321245
Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis., PMID:22005949
Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study., PMID:21742751
Collagen triple helix repeat containing-1 in the differential diagnosis of dermatofibrosarcoma protuberans and dermatofibroma., PMID:20849518
Intracellular localization of Cthrc1 characterizes differentiated smooth muscle., PMID:18467647