Catalog No.
PHA59502
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CYP26A1 (Lys361-Ile503).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
P450RAI1, Cytochrome P450 26A1, Cytochrome P450RAI, hP450RAI, CYP26A1, Cytochrome P450 retinoic acid-inactivating 1, Retinoic acid-metabolizing cytochrome, CYP26, Retinoic acid 4-hydroxylase
Purification
Purified by antigen affinity column.
Accession
O43174
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period., PMID:34712245
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy., PMID:27860312
Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction., PMID:26728457
Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1., PMID:24797530
The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer., PMID:24608339
Retinoic acid induces multiple hallmarks of the prospermatogonia-to-spermatogonia transition in the neonatal mouse., PMID:24478393
Retinoic acid regulation by CYP26 in vertebrate lens regeneration., PMID:24384390
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation., PMID:24325348
Cocaine decreases expression of neurogranin via alterations in thyroid receptor/retinoid X receptor signaling., PMID:22300446
The antitumor immunopreventive effects of a DNA vaccine against CYP26a1 on mouse breast carcinoma., PMID:21959331
FGF9 suppresses meiosis and promotes male germ cell fate in mice., PMID:20833365
Genetic analysis of expression profile involved in retinoid metabolism in non-alcoholic fatty liver disease., PMID:20618457
Targeting PKC delta-mediated topoisomerase II beta overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line., PMID:20200558
Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (cyp26a1) is essential for implantation: functional study of its role in early pregnancy., PMID:20112286
The role of CYP26 enzymes in retinoic acid clearance., PMID:19519282
The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes., PMID:19171200
The truncated Hoxa1 protein interacts with Hoxa1 and Pbx1 in stem cells., PMID:19115252
Epstein-Barr virus lytic infection induces retinoic acid-responsive genes through induction of a retinol-metabolizing enzyme, DHRS9., PMID:17244623
Skin retinoid concentrations are modulated by CYP26AI expression restricted to basal keratinocytes in normal human skin and differentiated 3D skin models., PMID:16778795
Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice., PMID:14623888
For research use only. Not for human or drug use.
