Catalog No.
PHB19401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human POLQ (Met1-Met894).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
POLH, DNA polymerase eta, DNA polymerase theta, POLQ
Purification
Purified by antigen affinity column.
Accession
O75417
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Analysis of translesion polymerases in colorectal cancer cells following cetuximab treatment: A network perspective., PMID:39102671
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ., PMID:25275444
DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken., PMID:20584917
Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes., PMID:16890500
DNA polymerases and somatic hypermutation of immunoglobulin genes., PMID:16319960
DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes., PMID:16172387
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells., PMID:14576298