Anti-Human TNIP1 Polyclonal Antibody

Catalog No.

PHG98101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TNIP1 (Glu2-Gln636).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Naf1, Virion-associated nuclear shuttling protein, VAN, TNFAIP3-interacting protein 1, KIAA0113, HIV-1 Nef-interacting protein, hVAN, A20-binding inhibitor of NF-kappa-B activation 1, Nef-associated factor 1, TNIP1, NAF1, Nip40-1, ABIN-1

Purification

Purified by antigen affinity column.

Accession

Q15025

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

A TNIP1-driven systemic autoimmune disorder with elevated IgG4., PMID:39060650

Myelin oligodendrocyte glycoprotein-associated disease is associated with BANK1, RNASET2 and TNIP1 polymorphisms., PMID:36054934

Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage., PMID:35077396

Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884

[Autoimmune diseases and ubiquitin system]., PMID:29367528

ABIN1 Determines Severity of Glomerulonephritis via Activation of Intrinsic Glomerular Inflammation., PMID:28935578

C/EBP β mRNA expression is upregulated and positively correlated with the expression of TNIP1/TNFAIP3 in peripheral blood mononuclear cells from patients with systemic lupus erythematosus., PMID:27698734

Upregulation of the C/EBP β LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus., PMID:27659348

Leukocyte Ig-Like receptor B1 restrains dendritic cell function through increased expression of the NF-κB regulator ABIN1/TNIP1., PMID:27129285

Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations., PMID:26562150

ABIN1 dysfunction as a genetic basis for lupus nephritis., PMID:23970121

Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome., PMID:23944604

Autoimmune associations and autoantibody screening show focused recognition in patient subgroups with generalized myasthenia gravis., PMID:23792059

Anti-interferon alpha treatment in SLE., PMID:23566912

Pharmacogenetics of psoriasis: HLA-Cw6 but not LCE3B/3C deletion nor TNFAIP3 polymorphism predisposes to clinical response to interleukin 12/23 blocker ustekinumab., PMID:23521149

Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX plus tumor necrosis factor inhibitor combined therapy., PMID:22753658

Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population., PMID:22087647

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity., PMID:21606507

TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population., PMID:20516000

hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase., PMID:16601202

Production and characterization of a monoclonal antibody specific to Nef-associated factor 1 (Naf1)/A20-binding inhibitor of NF-kappaB activation (ABIN-1)., PMID:16225425

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