Catalog No.
PHJ31201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DDB2 (Pro166-Met383).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Damage-specific DNA-binding protein 2,DNA damage-binding protein 2,UV-damaged DNA-binding protein 2,DDB2,UV-DDB 2,DDBb,DDB p48 subunit
Purification
Purified by antigen affinity column.
Accession
Q92466
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis., PMID:34584012
Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins., PMID:30504782
An improved method for the detection of nucleotide excision repair factors at local UV DNA damage sites., PMID:28185850
Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage., PMID:27642047
Differential DNA lesion formation and repair in heterochromatin and euchromatin., PMID:26717995
Monitoring repair of UV-induced 6-4-photoproducts with a purified DDB2 protein complex., PMID:24489677
A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication., PMID:24335308
Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair., PMID:23604128
Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab., PMID:23519658
Surface plasmon resonance (SPR) spectrometry as a tool to analyze nucleic acid-protein interactions in crude cellular extracts., PMID:21156963
DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation., PMID:16030353
Cross-resistance to death ligand-induced apoptosis in cisplatin-selected HeLa cells associated with overexpression of DDB2 and subsequent induction of cFLIP., PMID:15644494
For research use only. Not for human or drug use.
