Anti-SYNE2 Polyclonal Antibody

Catalog No.

PHJ30901

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SYNE2 (Glu6-Asp263).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Nuclear envelope spectrin repeat protein 2,KIAA1011,Protein NUANCE,KASH domain-containing protein 2,Nesprin-2,Syne-2,NUA,SYNE2,Synaptic nuclear envelope protein 2,Nucleus and actin connecting element protein,KASH2

Purification

Purified by antigen affinity column.

Accession

Q8WXH0

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression., PMID:31784980

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle., PMID:31578382

Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat., PMID:26502805

Nesprins: tissue-specific expression of epsilon and other short isoforms., PMID:24718612

Nesprin interchain associations control nuclear size., PMID:22653047

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement., PMID:21173262

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development., PMID:20108321

Autoantigens identified by screening a human heart cDNA library with acute rheumatic fever sera., PMID:19758136

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton., PMID:19596800

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton., PMID:16648470

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle., PMID:15671068

Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton., PMID:15093733

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues., PMID:11792814

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction., PMID:10878022

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