Catalog No.
PHJ30901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SYNE2 (Glu6-Asp263).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Nuclear envelope spectrin repeat protein 2,KIAA1011,Protein NUANCE,KASH domain-containing protein 2,Nesprin-2,Syne-2,NUA,SYNE2,Synaptic nuclear envelope protein 2,Nucleus and actin connecting element protein,KASH2
Purification
Purified by antigen affinity column.
Accession
Q8WXH0
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression., PMID:31784980
Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle., PMID:31578382
Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat., PMID:26502805
Nesprins: tissue-specific expression of epsilon and other short isoforms., PMID:24718612
Nesprin interchain associations control nuclear size., PMID:22653047
Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement., PMID:21173262
Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development., PMID:20108321
Autoantigens identified by screening a human heart cDNA library with acute rheumatic fever sera., PMID:19758136
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton., PMID:19596800
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton., PMID:16648470
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle., PMID:15671068
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton., PMID:15093733
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues., PMID:11792814
Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction., PMID:10878022