Chimeric virus-like particles of nodavirus displaying M2e of human and avian influenza A viruses as a potential dual-use vaccine: Inducing a broader immune response and protecting mice against viral infections., PMID:40286563
Dual roles of influenza B virus neuraminidase mRNA vaccine in enhancing cross-lineage protection by supplementing inactivated split vaccination., PMID:40265888
A strategy of enhancing the protective efficacy of seasonal influenza vaccines by providing additional immunity to neuraminidase and M2e., PMID:40139072
A novel method to assess antibody-dependent cell-mediated cytotoxicity against influenza A virus M2 in immunized murine models., PMID:40078727
Influenza 5xM2e mRNA lipid nanoparticle vaccine confers broad immunity and significantly enhances the efficacy of inactivated split vaccination when coadministered., PMID:40073270
A novel tetravalent influenza vaccine based on one chimpanzee adenoviral vector., PMID:40023902
Inserting CTL Epitopes of the Viral Nucleoprotein to Improve Immunogenicity and Protective Efficacy of Recombinant Protein against Influenza A Virus., PMID:39452110
Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human influenza A viruses., PMID:39341478
Protection against the H1N1 influenza virus using self-assembled nanoparticles formed by lumazine synthase and bearing the M2e peptide., PMID:38955082
UV-Inactivated rVSV-M2e-Based Influenza Vaccine Protected against the H1N1 Influenza Challenge., PMID:38812326
Cross-protective efficacy and safety of an adenovirus-based universal influenza vaccine expressing nucleoprotein, hemagglutinin, and the ectodomain of matrix protein 2., PMID:38714444
Cross-protection against influenza viruses by chimeric M2e-H3 stalk protein or multi-subtype neuraminidase plus M2e virus-like particle vaccine in ferrets., PMID:38685171
Generation of Broad Protection against Influenza with Di-Tyrosine-Cross-Linked M2e Nanoclusters., PMID:38623820
Supplementation of seasonal vaccine with multi-subtype neuraminidase and M2 ectodomain virus-like particle improves protection against homologous and heterologous influenza viruses in aged mice., PMID:38561077
Crossprotection induced by virus-like particles containing influenza dual-hemagglutinin and M2 ectodomain., PMID:38390688
An experimental universal swine influenza a virus (IAV) vaccine candidate based on the M2 ectodomain (M2e) peptide does not provide protection against H1N1 IAV challenge in pigs., PMID:38087714
An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses., PMID:37671994
A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein., PMID:37491224
VLPs containing stalk domain and ectodomain of matrix protein 2 of influenza induce protection in mice., PMID:36849974
Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins., PMID:36570769
A Recombinant VSV-Based Bivalent Vaccine Effectively Protects against Both SARS-CoV-2 and Influenza A Virus Infection., PMID:36069551
Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle., PMID:36006890
A single-shot vaccine approach for the universal influenza A vaccine candidate M2e., PMID:35320040
In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression., PMID:34253060
Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope., PMID:32882637
Comparative Analyses of the Antiviral Activities of IgG and IgA Antibodies to Influenza A Virus M2 Protein., PMID:32698456
Oral immunization with an attenuated Salmonella Gallinarum encoding the H9N2 haemagglutinin and M2 ectodomain induces protective immune responses against H9N2 infection in chickens., PMID:32483989
Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection., PMID:31921179
Double-Layered M2e-NA Protein Nanoparticle Immunization Induces Broad Cross-Protection against Different Influenza Viruses in Mice., PMID:31840437
Intragastric delivery of recombinant Lactococcus lactis displaying ectodomain of influenza matrix protein 2 (M2e) and neuraminidase (NA) induced focused mucosal and systemic immune responses in chickens., PMID:31518854
Evaluation of Protective Immunity of Peptide Vaccines Composed of a 15-mer N-terminal Matrix Protein 2 and a Helper T-Cell Epitope Derived from Influenza A Virus., PMID:31501717
A Universal Influenza Nanovaccine for "Mixing Vessel" Hosts Confers Potential Ability to Block Cross-Species Transmission., PMID:31267679
Improving Cross-Protection against Influenza Virus Using Recombinant Vaccinia Vaccine Expressing NP and M2 Ectodomain Tandem Repeats., PMID:31240620
Targeting M2e to DEC-205 induces an enhanced serum antibody-dependent heterosubtypic protection against influenza A virus infection., PMID:30955979
Intranasally administered polyethylenimine adjuvanted influenza M2 ectodomain induces partial protection against H9N2 influenza A virus infection in chickens., PMID:30885310
Super-resolution microscopy reveals significant impact of M2e-specific monoclonal antibodies on influenza A virus filament formation at the host cell surface., PMID:30872764
The Role of Matrix Protein 2 Ectodomain in the Development of Universal Influenza Vaccines., PMID:30715367
Heterosubtypic protection against avian influenza virus by live attenuated and chimeric norovirus P-particle-M2e vaccines in chickens., PMID:30691981
Enhancing the cross protective efficacy of live attenuated influenza virus vaccine by supplemented vaccination with M2 ectodomain virus-like particles., PMID:30685658
Chimeric protein consisting of 3M2e and HSP as a universal influenza vaccine candidate: from in silico analysis to preliminary evaluation., PMID:30382564
Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy., PMID:30261204
Passively transferred M2e-specific monoclonal antibody reduces influenza A virus transmission in mice., PMID:30179634
Influence of the Linking Order of Fragments of HA2 and M2e of the influenza A Virus to Flagellin on the Properties of Recombinant Proteins., PMID:29713522
CROSS-PROTECTIVE PROPERTIES OF AN INFLUENZA VACCINE BASED ON HBC4M2E RECOMBINANT PROTEIN., PMID:36494924
Intranasal Nanovaccine Confers Homo- and Hetero-Subtypic Influenza Protection., PMID:29430819
Intranasal vaccination with M2e5x virus-like particles induces humoral and cellular immune responses conferring cross-protection against heterosubtypic influenza viruses., PMID:29324805
Highly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection., PMID:28903071
Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challenge., PMID:28622575
Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection., PMID:28257797
Universal influenza virus vaccines and therapeutic antibodies., PMID:28216325