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Anti-Influenza A virus M2 ectodomain/M2e Antibody (Fab65)

Catalog #:   RVV23403 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, IF, WB
Accession: P06821
Overview

Catalog No.

RVV23403

Species reactivity

Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Matrix protein 2, Proton channel protein M2, M

Concentration

2.31 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06821

Applications

ELISA, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Fab65

Data Image
  • SDS-PAGE
    SDS PAGE for Fab65
References

Chimeric virus-like particles of nodavirus displaying M2e of human and avian influenza A viruses as a potential dual-use vaccine: Inducing a broader immune response and protecting mice against viral infections., PMID:40286563

Dual roles of influenza B virus neuraminidase mRNA vaccine in enhancing cross-lineage protection by supplementing inactivated split vaccination., PMID:40265888

A strategy of enhancing the protective efficacy of seasonal influenza vaccines by providing additional immunity to neuraminidase and M2e., PMID:40139072

A novel method to assess antibody-dependent cell-mediated cytotoxicity against influenza A virus M2 in immunized murine models., PMID:40078727

Influenza 5xM2e mRNA lipid nanoparticle vaccine confers broad immunity and significantly enhances the efficacy of inactivated split vaccination when coadministered., PMID:40073270

A novel tetravalent influenza vaccine based on one chimpanzee adenoviral vector., PMID:40023902

Inserting CTL Epitopes of the Viral Nucleoprotein to Improve Immunogenicity and Protective Efficacy of Recombinant Protein against Influenza A Virus., PMID:39452110

Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human influenza A viruses., PMID:39341478

Protection against the H1N1 influenza virus using self-assembled nanoparticles formed by lumazine synthase and bearing the M2e peptide., PMID:38955082

UV-Inactivated rVSV-M2e-Based Influenza Vaccine Protected against the H1N1 Influenza Challenge., PMID:38812326

Cross-protective efficacy and safety of an adenovirus-based universal influenza vaccine expressing nucleoprotein, hemagglutinin, and the ectodomain of matrix protein 2., PMID:38714444

Cross-protection against influenza viruses by chimeric M2e-H3 stalk protein or multi-subtype neuraminidase plus M2e virus-like particle vaccine in ferrets., PMID:38685171

Generation of Broad Protection against Influenza with Di-Tyrosine-Cross-Linked M2e Nanoclusters., PMID:38623820

Supplementation of seasonal vaccine with multi-subtype neuraminidase and M2 ectodomain virus-like particle improves protection against homologous and heterologous influenza viruses in aged mice., PMID:38561077

Crossprotection induced by virus-like particles containing influenza dual-hemagglutinin and M2 ectodomain., PMID:38390688

An experimental universal swine influenza a virus (IAV) vaccine candidate based on the M2 ectodomain (M2e) peptide does not provide protection against H1N1 IAV challenge in pigs., PMID:38087714

An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses., PMID:37671994

A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein., PMID:37491224

VLPs containing stalk domain and ectodomain of matrix protein 2 of influenza induce protection in mice., PMID:36849974

Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins., PMID:36570769

A Recombinant VSV-Based Bivalent Vaccine Effectively Protects against Both SARS-CoV-2 and Influenza A Virus Infection., PMID:36069551

Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle., PMID:36006890

A single-shot vaccine approach for the universal influenza A vaccine candidate M2e., PMID:35320040

In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression., PMID:34253060

Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope., PMID:32882637

Comparative Analyses of the Antiviral Activities of IgG and IgA Antibodies to Influenza A Virus M2 Protein., PMID:32698456

Oral immunization with an attenuated Salmonella Gallinarum encoding the H9N2 haemagglutinin and M2 ectodomain induces protective immune responses against H9N2 infection in chickens., PMID:32483989

Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection., PMID:31921179

Double-Layered M2e-NA Protein Nanoparticle Immunization Induces Broad Cross-Protection against Different Influenza Viruses in Mice., PMID:31840437

Intragastric delivery of recombinant Lactococcus lactis displaying ectodomain of influenza matrix protein 2 (M2e) and neuraminidase (NA) induced focused mucosal and systemic immune responses in chickens., PMID:31518854

Evaluation of Protective Immunity of Peptide Vaccines Composed of a 15-mer N-terminal Matrix Protein 2 and a Helper T-Cell Epitope Derived from Influenza A Virus., PMID:31501717

A Universal Influenza Nanovaccine for "Mixing Vessel" Hosts Confers Potential Ability to Block Cross-Species Transmission., PMID:31267679

Improving Cross-Protection against Influenza Virus Using Recombinant Vaccinia Vaccine Expressing NP and M2 Ectodomain Tandem Repeats., PMID:31240620

Targeting M2e to DEC-205 induces an enhanced serum antibody-dependent heterosubtypic protection against influenza A virus infection., PMID:30955979

Intranasally administered polyethylenimine adjuvanted influenza M2 ectodomain induces partial protection against H9N2 influenza A virus infection in chickens., PMID:30885310

Super-resolution microscopy reveals significant impact of M2e-specific monoclonal antibodies on influenza A virus filament formation at the host cell surface., PMID:30872764

The Role of Matrix Protein 2 Ectodomain in the Development of Universal Influenza Vaccines., PMID:30715367

Heterosubtypic protection against avian influenza virus by live attenuated and chimeric norovirus P-particle-M2e vaccines in chickens., PMID:30691981

Enhancing the cross protective efficacy of live attenuated influenza virus vaccine by supplemented vaccination with M2 ectodomain virus-like particles., PMID:30685658

Chimeric protein consisting of 3M2e and HSP as a universal influenza vaccine candidate: from in silico analysis to preliminary evaluation., PMID:30382564

Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy., PMID:30261204

Passively transferred M2e-specific monoclonal antibody reduces influenza A virus transmission in mice., PMID:30179634

Influence of the Linking Order of Fragments of HA2 and M2e of the influenza A Virus to Flagellin on the Properties of Recombinant Proteins., PMID:29713522

CROSS-PROTECTIVE PROPERTIES OF AN INFLUENZA VACCINE BASED ON HBC4M2E RECOMBINANT PROTEIN., PMID:36494924

Intranasal Nanovaccine Confers Homo- and Hetero-Subtypic Influenza Protection., PMID:29430819

Intranasal vaccination with M2e5x virus-like particles induces humoral and cellular immune responses conferring cross-protection against heterosubtypic influenza viruses., PMID:29324805

Highly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection., PMID:28903071

Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challenge., PMID:28622575

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection., PMID:28257797

Universal influenza virus vaccines and therapeutic antibodies., PMID:28216325

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Influenza A virus M2 ectodomain/M2e Antibody (Fab65) [RVV23403]
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