Research Grade Anti-Dog CD152/CTLA4 Antibody (12B3)

Catalog No.

DQD17201

Expression system

Mammalian Cells

Species reactivity

Dog

Host species

Dog

Isotype

IgG2, kappa

Clonality

Monoclonal

Target

Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9XSI1

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

12B3

Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors., PMID:34856888

Establishment of long-term tolerance to SRBC in dogs by recombinant canine CTLA4-Ig., PMID:19667932

[Evaluation of antigen specific IgE responses in Japanese asthmatics and non-asthmatics]., PMID:15672726

Autoantibodies against T-Cell costimulatory molecules are produced in canine autoimmune diseases., PMID:12514425

Molecular cloning and sequencing of canine T-cell costimulatory molecule (CD28)., PMID:11292534

Cloning and sequencing of dog cDNA encoding the T-cell costimulatory molecule (CTLA-4)., PMID:10663567

Prevention of immunotoxin-induced immunogenicity by coadministration with CTLA4Ig enhances antitumor efficacy., PMID:9366448

Document Download

Research Grade Anti-Dog CD152/CTLA4 Antibody (12B3).pdf