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Anti-Mouse JAG2 Polyclonal Antibody

Catalog #:   PMJ84001 Specific References (40) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9QYE5
Overview

Catalog No.

PMJ84001

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse JAG2 (Met27-Asn201).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein jagged-2, hJ2, Jagged2, JAG2

Purification

Purified by antigen affinity column.

Accession

Q9QYE5

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
References

Immunosuppressive JAG2+ tumor-associated neutrophils hamper PD-1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells., PMID:40120139

The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation., PMID:39585329

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages., PMID:38636522

Notch ligands are biomarkers of anti-TNF response in RA patients., PMID:37796367

Osteosarcoma-Associated Immune Genes as Potential Immunotherapy and Prognosis Biomarkers., PMID:37452172

Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease., PMID:35819850

Anti-Jagged-1 immunotherapy in cancer., PMID:35421813

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Relationship of Notch Signal, Surfactant Protein A, and Indomethacin in Cervix During Preterm Birth: Mast Cell and Jagged-2 May Be Key in Understanding Infection-mediated Preterm Birth., PMID:34927491

Delta-like 1-Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse., PMID:34438113

Tumour-associated neutrophils orchestrate intratumoural IL-8-driven immune evasion through Jagged2 activation in ovarian cancer., PMID:32778818

Overexpression of JAG2 is related to poor outcomes in oral squamous cell carcinoma., PMID:32250571

Precision medicine for human cancers with Notch signaling dysregulation (Review)., PMID:31894255

Notch Ligand Binding Assay Using Flow Cytometry., PMID:29333477

Genetic prediction of the effectiveness of biologics for psoriasis treatment., PMID:27129929

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung., PMID:26580007

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors., PMID:25564622

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth., PMID:25387766

Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling., PMID:23955600

Bone marrow-derived CD11b+Jagged2+ cells promote epithelial-to-mesenchymal transition and metastasization in colorectal cancer., PMID:23722542

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength., PMID:23530123

Jagged2-signaling promotes IL-6-dependent transplant rejection., PMID:23526606

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis., PMID:22652674

Expression of Notch receptors and ligands on immature and mature T cells., PMID:22310713

Notch-ligand expression by NALT dendritic cells regulates mucosal Th1- and Th2-type responses., PMID:22200492

MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate., PMID:20572854

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors., PMID:20161710

Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1., PMID:19598246

Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands., PMID:19181931

Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation., PMID:19171875

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud., PMID:16245338

Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines., PMID:15292061

Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1., PMID:15039222

Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts., PMID:14586405

Expression of Notch1 and Jagged2 in the enteric nervous system., PMID:12810847

Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells., PMID:12052893

Cortisol regulates the expression of Notch in osteoblasts., PMID:11948681

Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice., PMID:11841846

Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes., PMID:11700865

Human ligands of the Notch receptor., PMID:10079256

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Mouse JAG2 Polyclonal Antibody [PMJ84001]
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