Catalog No.
PMJ52001
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse REG4 (Gly32-Thr157).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Reg IV, Gastrointestinal secretory protein, REG-like protein, Regenerating islet-derived protein IV, REG-4, RELP, REG4, GISP, Regenerating islet-derived protein 4
Purification
Purified by antigen affinity column.
Accession
Q9D8G5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment., PMID:35742884
Single-chain Antibody Against Reg4 Suppresses Gastric Cancer Cell Growth and Enhances 5-FU-induced Cell Death in vitro., PMID:30465515
Reg IV is differently expressed in enteroendocrine cells of human small intestine and colon., PMID:23499801
Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers., PMID:22826614
Regenerating islet-derived family member, 4 modulates multiple receptor tyrosine kinases and mediators of drug resistance in cancer., PMID:21445968
Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma., PMID:21262260
Reg4 protects against acinar cell necrosis in experimental pancreatitis., PMID:21193457
Immunostaining of gastric cancer with neuroendocrine differentiation: Reg IV-positive neuroendocrine cells are associated with gastrin, serotonin, pancreatic polypeptide and somatostatin., PMID:20403031
REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study., PMID:20183800
REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells., PMID:20126989
Expression of Reg IV and Hath1 in neuroendocrine neoplasms., PMID:19924642
Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis., PMID:19900450
The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target., PMID:19834624
Expression profile of REG family proteins REG Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers., PMID:19329938
Reg IV protein is expressed in normal rat tissue., PMID:19138013
Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma., PMID:18580680
Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4., PMID:16918991
Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas., PMID:16401477
High expression of RELP (Reg IV) in neoplastic goblet cells of appendiceal mucinous cystadenoma and pseudomyxoma peritonei., PMID:16323007
Expression of a novel regenerating gene product, Reg IV, by high density fermentation in Pichia pastoris: production, purification, and characterization., PMID:14550637
For research use only. Not for human or drug use.
