Catalog No.
PMN41301
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse Pirb/Lilrb3 (Ile30-Gly316).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Paired immunoglobulin-like receptor B, Pirb, Lilrb3
Purification
Purified by antigen affinity column.
Accession
Q8K4V6
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The LILRB family in hematologic malignancies: prognostic associations, mechanistic considerations, and therapeutic implications., PMID:39696628
Strain-specific differences in reovirus infection of murine macrophages segregate with polymorphisms in viral outer-capsid protein σ3., PMID:39431846
Passive immunoprophylaxis with Ccombodies against Vibrio parahaemolyticus in Pacific white shrimp (Penaeus vannamei)., PMID:39426641
PirA- or PirB-binding nanobodies can protect whiteleg shrimp from the acute hepatopancreatic necrosis disease toxin., PMID:39387475
Development of Monoclonal Antibody against PirB and Establishment of a Colloidal Gold Immunochromatographic Assay for the Rapid Detection of AHPND-Causing Vibrio., PMID:38891648
Effects of porcine epidemic diarrhea virus infection on CD21+ B cells activation., PMID:38663176
Novel sandwich immunoassay detects a shrimp AHPND-causing binary PirABVp toxin produced by Vibrio parahaemolyticus., PMID:38089817
Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus., PMID:37147336
LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB., PMID:36510132
Involvement of Paired Immunoglobulin-Like Receptor B in Cognitive Dysfunction Through Hippocampal-Dependent Synaptic Plasticity Impairments in Mice Subjected to Chronic Sleep Restriction., PMID:36417104
Fabrication of lateral flow immunoassay strip for rapid detection of acute hepatopancreatic necrosis disease., PMID:36033912
Expression of the AHPND Toxins PirAvp and PirBvp Is Regulated by Components of the Vibrio parahaemolyticus Quorum Sensing (QS) System., PMID:35270031
Involvement of Paired Immunoglobulin-like Receptor B in Diabetes-Associated Cognitive Dysfunction Through Modulation of Axon Outgrowth and Dendritic Remodeling., PMID:35091963
Fine definition of the epitopes on the human gp91phox/NOX2 for the monoclonal antibodies CL-5 and 48., PMID:34971634
Potential genetic basis of B cell hyperactivation in murine lupus models., PMID:34000881
Production of polyclonal antibody against the recombinant PirBvp protein of Vibrio parahaemolyticus., PMID:33977321
ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation., PMID:33537094
Passive Immunization with Recombinant Antibody VLRB-PirAvp/PirBvp-Enriched Feeds against Vibrio parahaemolyticus Infection in Litopenaeus vannamei Shrimp., PMID:33467013
Development of an indirect Enzyme Linked Immunoassay (iELISA) using monoclonal antibodies against Photorhabdus insect related toxins, PirAVp and PirBVp released from Vibrio spp., PMID:32653400
Nogo receptor antagonist LOTUS exerts suppression on axonal growth-inhibiting receptor PIR-B., PMID:32201946
Therapeutic effects of soluble human leukocyte antigen G2 isoform in lupus-prone MRL/lpr mice., PMID:31733925
Anti-PirA-like toxin immunoglobulin (IgY) in feeds passively immunizes shrimp against acute hepatopancreatic necrosis disease., PMID:31115066
Nucleic Acid Vaccine Targeting Nogo-66 Receptor and Paired Immunoglobulin-Like Receptor B as an Immunotherapy Strategy for Spinal Cord Injury in Rats., PMID:30843154
MHC Class I Molecules and PirB Shape Neuronal Morphology by Affecting the Dendritic Arborization of Cortical Neurons., PMID:30406910
Inhibition of neurite outgrowth using commercial myelin associated glycoprotein-Fc in neuro-2a cells., PMID:30233061
Changes in Expressions of Major Histocompatibility Complex Class I, Paired-Immunoglobulin-Like Receptor B, and Cluster of Differentiation 3ζ in Motor Cortical Representations of the Brachial Plexus After Avulsion in Rats., PMID:28669876
Experimental and Clinical Advances in Immunotherapy Strategies for Spinal Cord Injury Target on MAIs and Their Receptors., PMID:26635269
Absence of sodA Increases the Levels of Oxidation of Key Metabolic Determinants of Borrelia burgdorferi., PMID:26322513
Neurotoxicity effects of atrazine-induced SH-SY5Y human dopaminergic neuroblastoma cells via microglial activation., PMID:26256823
HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats., PMID:26125554
PD-L1 blockade improves immune dysfunction of spleen dendritic cells and T-cells in zymosan-induced multiple organs dysfunction syndromes., PMID:25973021
Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN., PMID:25012177
[Neuroregeneration of newborn rats with hypoxic-ischemic brain damage following antibody-mediated neutralization of paired-immunoglobulin-like receptor B]., PMID:24461182
PirB is a novel potential therapeutic target for enhancing axonal regeneration and synaptic plasticity following CNS injury in mammals., PMID:24405091
PirB restricts neuronal regeneration in developing rat brain following hypoxia-ischemia., PMID:22580685
Lipopolysaccharide induces paired immunoglobulin-like receptor B (PirB) expression, synaptic alteration, and learning-memory deficit in rats., PMID:22395112
Oligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly., PMID:20980605
Role of PIR-B in autoimmune glomerulonephritis., PMID:20976309
Augmented TLR9-induced Btk activation in PIR-B-deficient B-1 cells provokes excessive autoantibody production and autoimmunity., PMID:19687229
PirB is a functional receptor for myelin inhibitors of axonal regeneration., PMID:18988857
PIR-B-deficient mice are susceptible to Salmonella infection., PMID:18768880
B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling., PMID:17717600
Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation., PMID:17420263
Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupus., PMID:16249245
Expression and modulation of an NADPH oxidase in mammalian astrocytes., PMID:16207877
Paired immunoglobulin-like receptors and their MHC class I recognition., PMID:16011512
HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors., PMID:15265899
[Regulation of B cell receptor signaling]., PMID:14748144
Mast cell regulation via paired immunoglobulin-like receptor PIR-B., PMID:12403357
Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression., PMID:11956299