Catalog No.
PMN41601
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse KIRREL1 (Thr51-Glu523).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NEPH1, KIRREL1, Kin of IRRE-like protein 1, KIRREL, Nephrin-like protein 1, Kin of irregular chiasm-like protein 1
Purification
Purified by antigen affinity column.
Accession
Q80W68
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Anti-slit Antibodies against Podocin and Kirrel1 in Pediatric and Adult Podocytopathies., PMID:39883528
Evolution of Fc Receptor-Like Scavenger in Mammals., PMID:33708190
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1-associated membranous nephropathy., PMID:33351779
Functional study of mammalian Neph proteins in Drosophila melanogaster., PMID:22792268
Comparative analysis of Neph gene expression in mouse and chicken development., PMID:22205279
Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis., PMID:21858180
Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin., PMID:21306299
Glomerular proteins related to slit diaphragm and matrix adhesion in the foot processes are highly tyrosine phosphorylated in the normal rat kidney., PMID:20067908
Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes., PMID:19515699
Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis., PMID:18715943
Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers., PMID:12646566